2010 Protein Folding Dynamics Gordon Research Conference and Seminar in Ventura, CA from January 9-15, 2010

2010 年蛋白质折叠动力学 Gordon 研究会议和研讨会于 2010 年 1 月 9 日至 15 日在加利福尼亚州文图拉举行

• 批准号: 0949243
• 负责人: Susan Marqusee
• 金额: $ 1.8万
• 依托单位: Gordon Research Conferences
• 依托单位国家: 美国
• 项目类别: Standard Grant
• 财政年份: 2009
• 资助国家: 美国
• 起止时间: 2009-12-01 至 2010-11-30
• 项目状态: 已结题
• 来源: https://www.nsf.gov/awardsearch/showAward?AWD_ID=0949243&HistoricalAwards=false
• 关键词: 2010; Protein; Folding; Dynamics; Gordon

The 5th Gordon Research Conference on Protein Folding Dynamics and the accompanying Graduate Research Seminar, which is a workshop for graduate students and post docs addressing the methods and models of protein folding will take place at the Ventura Beach Marriott,Ventura, California from January 9-10 (GRS) and January 10-15 (GRC), 2010. Funding from the NSF will allow a broad participation from both young and established scientists working in this field. Protein folding is a multidisciplinary area of research addressing fundamental problems in biology. Consequently, few other fields see such a successful blend of physical and biological sciences. Progressively, more studies that bring together experiment and theory are being published, and this combination is advancing our fundamental quantitative understanding of the information encoded within protein sequences. Technological and theoretical advances have altered our view of the protein folding and dynamics. Fast events can be observed experimentally on timescales that approach those accessible by all-atom molecular dynamics simulations. New,sophisticated models of proteins allow ensemble kinetics to be sampled and compared to experiment.The Gordon Research Conference in Protein Folding Dynamics, is a relatively new conference,first set up in 2002, aimed specifically to bring experiment and theory together to explore advances in the field and to serve as a forum to discuss fundamental problems from polypeptide energetics and dynamics; to chaperone assisted folding and the relationship between protein misfolding and disease.Broader Impacts: As the field matures and development in the physical sciences are being applied to important problems in protein dynamics and energetics, it becomes even more important to provide this venue to foster this communication and training at this interface between theory and experiment. The GRC fosters an environment that attracts the brightest and the most interactive members of the community. The ideas and hypotheses developed at this conference will continue to advance the field of protein folding dynamics as well as larger community interested in understanding the information encoded in protein sequences, fields as diverse as biomaterials to human genetics.The Graduate Research Seminar in Protein Folding Dynamics is a meeting being organized as a satellite to the GRC in Protein Folding Dynamics. This workshop serves as a venue for graduate students and postdoctoral scientists to i) develop background on current techniques, theories and models in preparation for the GRC in Protein Folding Dynamics, ii) share their knowledge of protein folding methodologies and techniques and iii) meet each other and discuss their own research. The involvement and inclusion of young and developing scientists represents a key objective in the vision of the conference to provide this vibrant multi-disciplinary research area with scientists who are broadly based in both experimental protein folding methodologies and the models and theories that provide a basis for the interpretation of experiment in this field.

第五届戈登研究会议蛋白质折叠动力学和随之而来的研究生研究研讨会，这是一个研讨会的研究生和博士后解决的方法和模型的蛋白质折叠将发生在文图拉海滩万豪酒店，文图拉，加州从1月9日至10日（GRS）和1月10日至15日（GRC），2010年。 来自NSF的资金将允许在这一领域工作的年轻和成熟科学家的广泛参与。蛋白质折叠是一个多学科的研究领域，解决生物学中的基本问题。因此，很少有其他领域看到物理和生物科学如此成功的融合。越来越多的研究将实验和理论结合在一起，这种结合正在推进我们对蛋白质序列中编码的信息的基本定量理解。技术和理论的进步改变了我们对蛋白质折叠和动力学的看法。快速事件可以在接近全原子分子动力学模拟的时间尺度上通过实验观察到。新的，复杂的蛋白质模型允许合奏动力学被采样和比较实验.戈登研究会议蛋白质折叠动力学，是一个相对较新的会议，首次成立于2002年，旨在专门把实验和理论一起探索在该领域的进展，并作为一个论坛，讨论从多肽能量学和动力学的基本问题;分子伴侣辅助折叠以及蛋白质错误折叠与疾病之间的关系。随着该领域的成熟和物理科学的发展正在被应用于蛋白质动力学和能量学中的重要问题，在理论和实验的这个界面上提供这个场所来促进这种交流和培训变得更加重要。GRC营造了一个吸引社区中最聪明和最具互动性的成员的环境。在这次会议上开发的想法和假设将继续推进蛋白质折叠动力学领域，以及有兴趣了解蛋白质序列编码信息的更大社区，从生物材料到人类遗传学领域。蛋白质折叠动力学研究生研究研讨会是一次会议，作为蛋白质折叠动力学GRC的卫星组织。该研讨会作为研究生和博士后科学家的一个场所，i）为蛋白质折叠动力学中的GRC做准备，发展当前技术，理论和模型的背景，ii）分享他们对蛋白质折叠方法和技术的知识，iii）互相见面并讨论自己的研究。年轻和发展中的科学家的参与和包容代表了会议愿景的一个关键目标，即为这个充满活力的多学科研究领域提供广泛基于实验蛋白质折叠方法以及模型和理论的科学家，这些模型和理论为解释该领域的实验提供了基础。