LSCBR: Chlamydomonas Resource Center

LSCBR：衣藻资源中心

• 批准号: 0951671
• 负责人: Paul Lefebvre
• 金额: $ 99.45万
• 依托单位: University of Minnesota-Twin Cities
• 依托单位国家: 美国
• 项目类别: Continuing Grant
• 财政年份: 2010
• 资助国家: 美国
• 起止时间: 2010-05-01 至 2016-06-30
• 项目状态: 已结题
• 来源: https://www.nsf.gov/awardsearch/showAward?AWD_ID=0951671&HistoricalAwards=false
• 关键词: LSCBR; Chlamydomonas; Resource; Center

Chlamydomonas reinhardtii has been a long standing model system in the biological sciences for studies of photosynthesis, flagellar development and other aspects of cell biology. Recently, as a fast-growing, photosynthetic eukaryote, Chlamydomonas has attracted a great deal of interest as a source of biomass and renewable energy. University of Minnesota-Twin Cities houses the Chlamydomonas Resource Center (CRC) and its utility is enhanced by the availability of the sequence of the nuclear, chloroplast and mitochondrial genomes. CRC has a large collection of mutants and a complete genetic map linked to the molecular map. The PI serves as the new Director of CRC and, in its 30th year of operation, this stock collection center will continue to act as the central repository to receive, catalogue, preserve and distribute wild type and mutant cultures of C. reinhardtii. The Center will continue to maintain and distribute molecular tools for Chlamydomonas research, including genomic and cDNA clones of Chlamydomonas nuclear, chloroplast and mitochondrial genes, and cDNA libraries. The Center will continue to distribute teaching kits, with reagents, strains and instructions for high school and beginning college biology class experiments. A web site [http://www.chlamy.org] will provide descriptions of all cultures in the collection, historical information and reference material on genetic loci and mutant alleles, genetic and molecular maps, and an extensive bibliography.

莱茵衣藻（Chlamydomonas reinhardtii）是生物科学中研究光合作用、鞭毛发育和其他细胞生物学方面的一个长期存在的模型系统。近年来，衣藻作为一种快速生长的光合真核生物，作为生物质和可再生能源的来源引起了人们的极大兴趣。明尼苏达大学双城分校是衣藻资源中心（CRC）的所在地，其效用因核、叶绿体和线粒体基因组序列的可用性而得到增强。CRC有大量的突变体和完整的遗传图谱与分子图谱相连。PI将担任该中心的新主任，在其运营的第30个年头，该库存收集中心将继续作为中央存储库，接收、编目、保存和分发野生型和突变型莱茵哈蒂菌。该中心将继续维护和分发用于衣藻研究的分子工具，包括衣藻细胞核、叶绿体和线粒体基因的基因组和cDNA克隆，以及cDNA文库。该中心将继续为高中和大学初级班的生物实验分发教学包，包括试剂、菌株和说明。一个网站[http://www.chlamy.org]]将提供收集的所有文化的描述、遗传位点和突变等位基因的历史信息和参考资料、遗传和分子图谱以及广泛的参考书目。