Chlamydomonas Resource Center

衣藻资源中心

• 批准号: 0444335
• 负责人: Paul Lefebvre
• 金额: $ 104.84万
• 依托单位: University of Minnesota-Twin Cities
• 依托单位国家: 美国
• 项目类别: Continuing Grant
• 财政年份: 2005
• 资助国家: 美国
• 起止时间: 2005-07-15 至 2010-03-31
• 项目状态: 已结题
• 来源: https://www.nsf.gov/awardsearch/showAward?AWD_ID=0444335&HistoricalAwards=false
• 关键词: Chlamydomonas; Resource; Center

Project Summary This award renews support for a collection of 2300 strains of the unicellular green alga consisting of mutants of C. reinhardtii and closely related species. Chlamydomonas is an excellent model system for studies of photosynthesis, flagellar biogenesis and function, signal transduction, and other aspects of cell biology. The recent completion of the genome sequence of Chlamydomonas will likely accelerate the adoption of this organism as an experimental tool. The collection, now called the Chlamydomonas Resource Center (formerly, the Chlamydomonas Genetics Center at Duke University), serves as the central repository to receive, catalogue, preserve and distribute wild type and mutant cultures of C. reinhardtii and other Chlamydomonas species in which extensive genetic analysis has been done. It also serves as the resource center to disseminate information on this organism to the international scientific community. Given its ease of culture and striking flagellar motility, Chlamydomonas is also an ideal organism for laboratory exercises for high school students and college undergraduates. Thus, the Center also provides materials and advice for students and teachers interested in adopting Chlamydomonas for classroom and individual science projects. In addition to live cultures, the Center also maintains and distributes molecular reagents useful for research on Chlamydomonas, including genomic and cDNA clones of Chlamydomonas nuclear, chloroplast and mitochondrial genes, and cDNA libraries. A web site [http://www.chlamy.org] provides descriptions of all cultures in the collection, historical information and reference material on genetic loci and mutant alleles, genetic and molecular maps, an address directory, and an extensive bibliography.

该奖项重申了对2300株单细胞绿藻的支持，这些绿藻由C. reinhardtii的突变体和密切相关的物种组成。衣单胞菌是研究光合作用、鞭毛生物发生与功能、信号转导等细胞生物学方面的优秀模型系统。最近完成的衣藻基因组序列可能会加速采用这种有机体作为实验工具。该收藏现在被称为衣藻资源中心（以前是杜克大学衣藻遗传中心），作为中央储存库，接收、编目、保存和分发莱因哈特衣藻和其他衣藻物种的野生型和突变培养物，并对其进行了广泛的遗传分析。它还作为向国际科学界传播关于这种生物的信息的资源中心。由于其易于培养和惊人的鞭毛运动性，衣藻也是高中生和大学本科生实验室练习的理想生物。因此，该中心还为有兴趣在课堂和个人科学项目中采用衣藻的学生和教师提供材料和建议。除了活体培养外，该中心还维护和分发对衣藻研究有用的分子试剂，包括衣藻细胞核、叶绿体和线粒体基因的基因组和cDNA克隆，以及cDNA文库。一个网站[http://www.chlamy.org]]提供了收集的所有文化的描述，历史信息和遗传位点和突变等位基因的参考资料，遗传和分子地图，地址目录和广泛的参考书目。