MRI-R2: Acquisition of a Scanning Electron Microscope (SEM) and Atomic Force Microscope (AFM) for a Multidisciplinary Core Imaging Facility

MRI-R2：为多学科核心成像设施采购扫描电子显微镜 (SEM) 和原子力显微镜 (AFM)

• 批准号: 0959168
• 负责人: Aric Opdahl
• 金额: $ 52.41万
• 依托单位: University of Wisconsin-La Crosse
• 依托单位国家: 美国
• 项目类别: Standard Grant
• 财政年份: 2010
• 资助国家: 美国
• 起止时间: 2010-02-01 至 2013-01-31
• 项目状态: 已结题
• 来源: https://www.nsf.gov/awardsearch/showAward?AWD_ID=0959168&HistoricalAwards=false
• 关键词: MRI; R2; Acquisition; Scanning; Electron

This award is funded under the American Recovery and Reinvestment Act of 2009 (Public Law 111-5).With this award from the Major Research Instrumentation (MRI) program, the Departments of Chemistry, Biology, Microbiology, and Physics at the University of Wisconsin - La Crosse will acquire a Scanning Electron Microscope (SEM) and Atomic Force Microscope (AFM) to support research activities in these Departments. This instrumentation will significantly expand the capabilities of the University's Core Imaging Facility. Examples of specific projects that will use the requested instrumentation include: 1) the investigation of the structure and stability of DNA films on gold surfaces, 2) the investigation of organic/inorganic semiconductor interfaces, 3) the investigation of the structural and functional properties of full-length hemolysin A, 4) the use of semiconductor quantum dots to detect single photons, 5) the quantifying of particulate food resources in the upper Mississippi River as a means of evaluating the impacts of invasive species , 6) the analysis of the phenotype of defective cell cycle genes in Saccharomyces cerevisiae meiosis, as well as the research projects of seven additional faculty in these Departments. The instrumentation will be available to a large number of undergraduate students -- both students enrolled in laboratory courses as well as undergraduate researchers. This group includes a significant number of students from underrepresented groups. In addition, the SEM and AFM will feature prominently in a number of extramural collaborations between research groups on campus and external partners.Scanning electron microscopy and atomic force microscopy are widely used techniques for providing an image of a sample surface. The image is obtained by scanning an electron beam (SEM) or an atomically-sharp tip (AFM) over the surface under study. The resolution obtainable with both SEM and AFM microscopies (ca. nanometer or less) is significantly better than that achievable with optical microscopes. The instruments acquired will be housed in the University's Core Imaging Facility, and will be used by researchers from a wide variety of science disciplines.

该奖项是根据2009年美国复苏和再投资法案（公法111-5）。从主要研究仪器（MRI）计划，化学，生物学，微生物学和物理学在威斯康星州-拉克罗斯大学的部门这一奖项将获得扫描电子显微镜（SEM）和原子力显微镜（AFM），以支持这些部门的研究活动。 这种仪器将大大扩大该大学核心成像设施的能力。 将使用所要求的工具的具体项目示例包括：1）研究金表面上DNA膜的结构和稳定性，2）研究有机/无机半导体界面，3）研究全长溶血素A的结构和功能性质，4）使用半导体量子点检测单光子，5）在上游密西西比河颗粒食物资源的量化作为评估入侵物种的影响的一种手段，6）在酿酒酵母减数分裂缺陷细胞周期基因的表型分析，以及在这些部门的其他七个教师的研究项目。 该仪器将提供给大量的本科生-无论是在实验室课程注册的学生，以及本科研究人员。 该群体包括大量来自代表性不足群体的学生。 此外，SEM和AFM将在校园研究小组和外部合作伙伴之间的一些校外合作中发挥重要作用。扫描电子显微镜和原子力显微镜是广泛使用的提供样品表面图像的技术。 该图像是通过扫描电子束（SEM）或原子尖（AFM）在研究中的表面。 分辨率与SEM和AFM显微镜（约。纳米或更小）明显优于用光学显微镜可实现的。 获得的仪器将被安置在大学的核心成像设施，并将由来自各种科学学科的研究人员使用。