MRI-R2: Acquisition of Applied Biosystems SOLiD 3 System for Research and Education

该奖项是根据2009年美国复苏和再投资法案（公法111-5）资助的。NSF MRI-R2计划的资金已被授予康涅狄格大学，以支持购买应用生物系统SOLiD 3大规模并行核酸测序仪。 新的测序仪支持广泛的传统和非传统模式生物的研究工作，解决生态学，进化生物学，发育生物学，癌症生物学和分子遗传学的前沿问题。 该仪器的20个主要用户是一个非收费服务的用户联盟，应用遗传学和技术中心（CAGT）的一部分。 CAGT成员使用SOLiD 3仪器和数据进行从K-12教育到博士后培训的培训和推广活动。 SOLiD 3培训已被添加为非常成功的课程“高通量基因组分析的理论与实践”的一个新部分，并用于为教职员工和研究生提供实践培训。 CAGT提供援助，以支持将在此MRI下获得的现代基因组学技术纳入每年夏天为高中生提供的UConn Mentor Connection计划所涉及的研究站点，并在Mentor Connection期间提供为期一天的研讨会，向学生介绍下一代测序平台促进的“基因组学研究的未来”。 除了通过NSF AGEP和PSM计划在康州大学CAGT中的合作积极参与招募少数民族到STEM学科之外，该仪器还将用于与非传统模型系统会议中的下一代测序相关的计划研讨会。 收购SOLiD 3通过培训未来的科学家在这项技术，上游分子技术和下游数据分析进一步增强了劳动力。 研究和推广工作的结果将通过同行评审的期刊出版物以及学生和教师在区域和国家会议上的演讲进行传播。

This award is funded under the American Recovery and Reinvestment Act of 2009 (Public Law 111-5). Funds from the NSF MRI-R2 program have been awarded to the University of Connecticut to support the purchase of an Applied Biosystems SOLiD3 massively parallel nucleic acid sequencer. The new sequencer supports research endeavors in a broad range of traditional and non-traditional model organisms addressing questions at the forefront of ecology, evolutionary biology, developmental biology, cancer biology and molecular genetics. The 20 primary users of the instrument are part of a non-fee-for-service consortium of users, the Center for Applied Genetics and Technology (CAGT). The CAGT members use the SOLiD3 instrument and data in training and outreach activities from K-12 education through postdoctoral training. SOLiD3 training has been added as a new section to the highly successful course "Theory and Practice of High-Throughput Genome Analysis", and is used to provide hands-on training for faculty, staff and graduate students. The CAGT provides assistance to support the inclusion of modern genomics technology acquired under this MRI into the research sites involved in the UConn Mentor Connection program for high school students each summer and offers a one day workshop during the Mentor Connection period to introduce students to the "future of genomics research" facilitated by next generation sequencing platforms. In addition to active involvement in recruiting minorities to STEM disciplines through such collaborations as the NSF AGEP and PSM programs in the CAGT at UConn, the instrumentation will be used in a planned workshop associated with the Next Generation Sequencing in Non-Traditional Model Systems conference. The acquisition of the SOLiD3 further enhances the workforce through training future scientists in this technology, upstream molecular techniques and downstream data analysis. Results from the research and outreach efforts will be disseminated through peer-reviewed journal publications, and through student and faculty presentations at regional and national meetings.