MRI-R2: 120 kV Electron Microscope System for Sample Preparation, Biological Microscopy, Tomography, and Visualization of Protein Complexes

MRI-R2：120 kV 电子显微镜系统，用于蛋白质复合物的样品制备、生物显微镜、断层扫描和可视化

• 批准号: 0959745
• 负责人: Brian Storrie
• 金额: $ 149.11万
• 依托单位: University of Arkansas Medical Sciences Campus
• 依托单位国家: 美国
• 项目类别: Standard Grant
• 财政年份: 2010
• 资助国家: 美国
• 起止时间: 2010-01-15 至 2012-12-31
• 项目状态: 已结题
• 来源: https://www.nsf.gov/awardsearch/showAward?AWD_ID=0959745&HistoricalAwards=false
• 关键词: MRI; R2; 120; kV; Electron

This award is funded under the American Recovery and Reinvestment Act of 2009 (Public Law 111-5).This Major Research Instrumentation-Recovery and Reinvestment (MRI-R2) award funds the acquisition of a 120 kV electron microscopy system and supporting sample preparation equipment at the University of Arkansas Medical Sciences Campus(UAMS). The equipment is tailored to the needs of a group of basic scientists in the Departments of Physiology and Biophysics, Biochemistry and Molecular Biology, and Neurobiology and Developmental Sciences at UAMS. The new microscope is also accessible to investigators at other regional institutions. This acquisition is a major step toward establishing the only such biological electron microscope facility in the state of Arkansas. Research utilizing the new system includes studies to understand elements of virology, golgi apparatus function, neuronal physiology, endocrine secretion, and many more topics. Both undergraduate and graduate students will benefit from the acquisition of this instrumentation as investigators are engaged in the training of Ph.D. students in research, and each summer there is significant participation of undergraduates in the collaborating laboratories. Results from the studies enabled by the new instrumentation will be disseminated in peer-reviewed journals, and through students and faculty presentations at regional and national meetings.

该奖项根据 2009 年《美国复苏与再投资法案》（公法 111-5）提供资金。这项重大研究仪器-回收与再投资 (MRI-R2) 奖项资助在阿肯色大学医学科学校区 (UAMS) 购买 120 kV 电子显微镜系统和配套样品制备设备。该设备专为满足 UAMS 生理学和生物物理学、生物化学和分子生物学、神经生物学和发育科学系基础科学家的需求而定制。 其他地区机构的研究人员也可以使用这种新显微镜。此次收购是朝着在阿肯色州建立唯一的此类生物电子显微镜设施迈出的重要一步。利用新系统的研究包括了解病毒学要素、高尔基体功能、神经元生理学、内分泌分泌以及更多主题的研究。 由于研究人员正在从事博士培训，本科生和研究生都将从购买该仪器中受益。每年夏天，合作实验室都有大量本科生参与。 新仪器的研究结果将在同行评审期刊上传播，并通过学生和教师在地区和国家会议上的演讲进行传播。