MRI-R2: Acquisition of a SAXS/MAXS/WAXS Detector System for Nanoscale Studies of Soft Materials

MRI-R2：获取用于软材料纳米级研究的 SAXS/MAXS/WAXS 探测器系统

• 批准号: 0960140
• 负责人: Wesley Burghardt
• 金额: $ 75.54万
• 依托单位: Northwestern University
• 依托单位国家: 美国
• 项目类别: Standard Grant
• 财政年份: 2010
• 资助国家: 美国
• 起止时间: 2010-02-01 至 2013-09-30
• 项目状态: 已结题
• 来源: https://www.nsf.gov/awardsearch/showAward?AWD_ID=0960140&HistoricalAwards=false
• 关键词: MRI; R2; Acquisition; SAXS; MAXS

0960140BurghardtNorthwestern U.ABSTRACT (TECHNICAL)This award is funded under the American Recovery and Reinvestment Act of 2009 (Public Law 111-5). X-ray scattering and diffraction methods are powerful tools for studying the structure of soft materials on length scales ranging from ~ 0.1 to 100 nm. NSF MRI-R2 funds will support acquisition and commissioning of a unique small-, medium- and wide-angle (SAXS/MAXS/WAXS) detector system to be installed at Beamline 5ID-D at the Advanced Photon Source of Argonner National Laboratory. The new detector systems will offer unprecedented capabilities, including: (i) seamless coverage of ?reciprocal space? spanning three orders of magnitude in length scale; (ii) access to full two-dimensional scattering data over the entire accessible range of scattering vector; (iii) substantial upgrades in sensitivity and frame rate over currently available detectors, enabling the full potential afforded by APS undulator radiation to be harnessed; and (iv) significant improvements in operational efficiency, as a single, stable, end-station configuration meets the needs of the vast majority of 5ID-D users, avoiding disruptive layout changes. This consortium effort will be led by investigators from Northwestern in partnership with colleagues from the University of Minnesota who are major ?General Users? of 5ID-D. The new detector capabilities will favorably impact research in diverse areas such as dynamics and processing of polymers and other complex fluids; nano-scale DNA-mediated self-assembly processes; biophysical studies of protein/nucleic acid and protein/lipid complexes; block copolymer physics; polymer deformation; nanomaterials for solar energy conversion and catalysis; polymer membrane characterization; biomimetic self-assembly and biomineralization. Through the General User program of the Advanced Photon Source, this powerful instrumentation will be made available to the entire US x-ray scattering community, and thereby contribute to the nation?s research infrastructure, and to the education and training of a large number of students and post doctoral researchers. MRI-R2 CONSORTIUM: ACQUISITION OF A SAXS/MAXS/WAXS DETECTOR SYSTEM FOR NANOSCALE STUDIES OF SOFT MATERIALSProposal #0960140Wesley Burghardt, Chad Mirkin, Alfonso Mondragon Northwestern UniversityFrank S. Bates and Timothy P. Lodge University of MinnesotaABSTRACT (NONTECHNICAL)This award is funded under the American Recovery and Reinvestment Act of 2009 (Public Law 111-5). National ?User Facilities? form a vital infrastructure supporting US competitiveness in science, engineering and technology. By providing researchers access to cutting edge experimental capabilities, such facilities also contribute materially to the education and training of a sophisticated scientific workforce. The premier facility for x-ray science in the western hemisphere is the Advanced Photon Source (APS), located at Argonne National Laboratory. The APS generates extremely intense x-ray beams that may be used in many ways to study fundamental problems in biology, chemistry, physics, materials, and technology. One class of techniques, known as ?x-ray scattering?, involves measuring the way in which a beam of x-rays is deflected or ?scattered? by a sample?s microscopic internal structure. Analysis of scattering images provides deep insights into a sample?s structure over length scales from ~ 0.1 nm (the size of atoms) to ~ 100 nm (the size of very large molecules such as proteins). In this project, MRI-R2 funds will be used for the acquisition and commissioning of a new detector system to be installed at the Advanced Photon Source to greatly enhance capabilities for x-ray scattering research. Detectors are the ?cameras? that collect scattering images, and hence are at the heart of x-ray scattering techniques. The unique system being developed in this project will combine three separate detectors that will enable simultaneous investigation of samples? structure over the entire range of length scales studied using x-ray scattering (by anaology, imagine a camera that can simultaneously take a high quality picture of both a dog and a flea sitting on the dog?s back). The detectors will also operate at much higher speed than currently available systems, allowing ?real time? studies of molecular and nano-scale structural dynamics. Through its installation at the Advance Photon Source, these new capabilities will be made available scientists from all over the US, and used for studies of fundamental problems in biology, nanoscience and chemistry, as well as in technologically-oriented work in the characterization and processing of polymers catalysts, and other engineering materials.

0960140伯格哈特西北大学摘要（技术）这个奖项是根据2009年美国复苏和再投资法案（公法111-5）资助。X射线散射和衍射方法是研究软材料结构的有力工具，其长度范围为~ 0.1至100 nm。NSF的MRI-R2基金将支持一个独特的小、中、广角（SAXS/MAXS/WAXS）探测器系统的采购和调试，该系统将安装在阿贡纳国家实验室先进光子源的光束线5ID-D上。 新的探测器系统将提供前所未有的能力，包括：（一）无缝覆盖？相互空间？在长度尺度上跨越三个数量级;（ii）在散射矢量的整个可访问范围内获得完整的二维散射数据;（iii）在灵敏度和帧速率方面大大提高现有探测器，从而能够利用APS波荡器辐射提供的全部潜力;以及（iv）运营效率的显著提高，因为单一、稳定的终端站配置满足了绝大多数5ID-D用户的需求，避免了破坏性的布局变化。 这个联盟的工作将由西北大学的研究人员与明尼苏达大学的同事合作领导。一般用户？5ID-D。 新的探测器能力将有利地影响不同领域的研究，如聚合物和其他复杂流体的动力学和加工;纳米级DNA介导的自组装过程;蛋白质/核酸和蛋白质/脂质复合物的生物物理研究;嵌段共聚物物理学;聚合物变形;太阳能转换和催化的纳米材料;聚合物膜表征;仿生自组装和生物矿化。 通过高级光子源的一般用户计划，这种强大的仪器将提供给整个美国的X射线散射社区，从而为国家做出贡献？的研究基础设施，并教育和培养了大量的学生和博士后研究人员。MRI-R2联合体：获得SAXS/MAXS/WAXS检测器系统用于软吸收的纳米级研究提案#0960140 Wesley Burghardt，Chad Mirkin，阿方索蒙德拉贡西北大学Frank S.明尼苏达大学贝茨和蒂莫西·P·洛奇（非技术）该奖项是根据2009年美国复苏和再投资法案（公法111-5）资助的。全国？用户设施？形成支持美国在科学、工程和技术方面竞争力的重要基础设施。 通过向研究人员提供最先进的实验能力，这些设施还为教育和培训一支先进的科学队伍作出了重大贡献。 位于阿贡国家实验室的先进光子源（APS）是西半球X射线科学的首要设施。 APS产生极强的X射线束，可以以多种方式用于研究生物学，化学，物理学，材料和技术中的基本问题。 一种技术，称为？X射线散射包括测量X射线束被偏转的方式，或者？分散？一个样本？的微观内部结构。 散射图像的分析提供了深入的了解样品？的结构长度范围从~ 0.1 nm（原子的大小）到~ 100 nm（非常大的分子，如蛋白质的大小）。 在该项目中，MRI-R2资金将用于购买和调试安装在高级光子源的新探测器系统，以大大提高X射线散射研究的能力。 侦探是什么？摄像头收集散射图像，因此是X射线散射技术的核心。 该项目正在开发的独特系统将联合收割机结合三个独立的探测器，使样品的同时调查？使用X射线散射研究整个长度范围内的结构（通过解剖学，想象一下一台相机可以同时拍摄狗和坐在狗身上的跳蚤的高质量照片？s back）。 探测器的运行速度也将远远高于目前可用的系统，允许？真实的时间？分子和纳米尺度结构动力学的研究。 通过在先进光子源的安装，这些新功能将提供给来自美国各地的科学家，并用于生物学，纳米科学和化学中的基本问题的研究，以及在聚合物催化剂和其他工程材料的表征和加工中的技术导向工作。