Polyborane Syntheses and Reactions

化学合成(SYN)项目的这一奖项支持宾夕法尼亚大学的Larry G.Sneddon教授开展基础研究，开发新的通用方法，使具有重要技术意义的聚硼烷化合物、聚合物和材料的高产量合成成为可能。该项目的独特方法使用离子液体和/或过渡金属催化剂的激活效应来诱导选择性的聚硼烷转化。该项目既强调发现新的反应，也强调阐明其基本机理和控制因素，从而为将这些方法应用于广泛的聚硼烷和聚硼烷反应奠定了合理的基础。拟议工作的更广泛影响包括开发新的方法，使功能取代的聚硼烷、聚硼烷-金属络合物和聚(有机硼烷)聚合物的系统合成成为可能，这些聚合物可能作为医药剂、高温聚合物、烧伤率调节剂、核废料萃取剂、陶瓷前体和弱配位阴离子。该项目对金属有机化学、催化、药物化学、材料科学和替代能源研究相关领域产生强烈影响，从而为不同的本科生、研究生和博士后提供跨学科的培训。

This award in the Chemical Synthesis (SYN) program supports work by Professor Larry G. Sneddon at the University of Pennsylvania to carry out fundamental studies on the development of new general methodologies that enable the high-yield syntheses of technologically important polyborane compounds, polymers and materials. The project's unique approach uses the activating effects of ionic-liquids and/or transition metal catalysts to induce selective polyborane transformations. The project emphasizes both the discovery of new reactions and an elucidation of their fundamental mechanisms and controlling factors so that a rational basis for applying these methods to a wide range of polyboranes and polyborane reactions is achieved. The broader impacts of the proposed work include the development of new methods for enabling the systematic syntheses of functionally-substituted polyboranes, polyborane-metal complexes and poly(organoborane) polymers that have potential applications as medical agents, high temperature polymers, burn rate modifiers, extractants for nuclear wastes, ceramic precursors and weakly coordinating anions.This project strongly impacts the related fields of organometallic chemistry, catalysis, medicinal chemistry, materials science and alternative energy research and thereby provides interdisciplinary training to a diverse group of undergraduate, graduate, and postdoctoral students.