Biomechanical and Biochemical Mechanisms for Patterns on Plants
植物模式的生物力学和生化机制
基本信息
- 批准号:1022635
- 负责人:
- 金额:$ 13.13万
- 依托单位:
- 依托单位国家:美国
- 项目类别:Standard Grant
- 财政年份:2010
- 资助国家:美国
- 起止时间:2010-10-01 至 2014-09-30
- 项目状态:已结题
- 来源:
- 关键词:
项目摘要
Morphogenesis in biological systems involves interacting biochemical and biophysical mechanisms that operate at a range of temporal and spatial scales. In particular, recent experiments indicate that phyllotactic patterns (the arrangement and shapes of leaf buds at plant apices) arise from nonhomogeneous growth controlled by multiple mechanisms. This work develops models for phyllotactic patterning based on experimental insights on the interaction between biochemistry and biomechanics in plant morphogenesis, and derives equations governing defects in phyllotactic patterns. Data will be gathered on the shape of leaf buds, wavelet methods applied to analyze the patterns, the model tested experimentally with gels that mimic biological growth, and the packing properties of the patterns studied. Models for the growth of individual plant cells will also be extended to models for the growth of cells in tissue. Mathematical techniques involved include multiple scales analysis and tools from dynamical systems theory. Collaborators include Isaac Chenchiah, Todd Cooke, and Alan Newell.Biologists are becoming increasingly aware that mechanical stimuli interact with biochemical pathways in plants as well as animals. Clarifying the mechanisms and properties of these intricate interactions, while experimentally very challenging, has the potential to impact our understanding of many physiological processes. This project focuses on modeling the biochemical and biomechanical processes involved in the patterning of leaf buds at plant apices, a topic that has intrigued scientists for centuries and that is currently the subject of much experimental work. Patterns observed on plants present unique variations on planforms of ripples, hexagons, or squares observed in many laboratory and natural systems such as cloud formations, animal coats, and fluid convection experiments. These variations provide us with potential clues on the competition and cooperation between mechanisms. The modeling and mathematical analysis is complemented by the development of simple experimental systems in which the models can be tested on gels in a laboratory, with more control over parameters than in biological systems. The involvement of undergraduate and graduate students is an integral part of both the theoretical and experimental components of the project.
生物系统中的形态发生涉及在一系列时间和空间尺度上相互作用的生物化学和生物物理机制。特别是,最近的实验表明,叶序模式(叶芽在植物顶端的排列和形状)产生于由多种机制控制的非均匀生长。 这项工作开发的phyllotractic图案的基础上,在植物形态发生的生物化学和生物力学之间的相互作用的实验见解模型,并推导出方程的缺陷phyllotractic模式。 数据将收集叶芽的形状,小波方法应用于分析模式,模拟生物生长的凝胶实验测试的模型,以及研究的模式的包装特性。 单个植物细胞生长的模型也将扩展到组织中细胞生长的模型。 所涉及的数学技术包括多尺度分析和动力系统理论的工具。 合作者包括Isaac Chenchiah,托德库克和艾伦纽韦尔。生物学家越来越意识到,机械刺激与植物以及动物的生化途径相互作用。 澄清这些复杂相互作用的机制和性质,虽然在实验上非常具有挑战性,但有可能影响我们对许多生理过程的理解。 该项目的重点是模拟植物顶端叶芽图案中所涉及的生物化学和生物力学过程,这是一个几个世纪以来吸引科学家的话题,目前是许多实验工作的主题。 在植物上观察到的图案呈现出独特的变化,在许多实验室和自然系统中观察到的波纹,六边形或正方形的平面形状,如云的形成,动物外套和流体对流实验。 这些变化为我们研究机制之间的竞争与合作提供了潜在的线索。 通过开发简单的实验系统来补充建模和数学分析,在实验室中可以在凝胶上测试模型,对参数的控制比在生物系统中更多。 本科生和研究生的参与是该项目的理论和实验组成部分的一个组成部分。
项目成果
期刊论文数量(0)
专著数量(0)
科研奖励数量(0)
会议论文数量(0)
专利数量(0)
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Patrick Shipman其他文献
The dynamic behavior of bacterial macrofibers growing with one end prevented from rotating: variation in shaft rotation along the fiber's length, and supercoil movement on a solid surface toward the constrained end
- DOI:
10.1186/1471-2180-3-18 - 发表时间:
2003-08-16 - 期刊:
- 影响因子:4.200
- 作者:
Neil H Mendelson;Patrick Shipman;Darshan Roy;Liling Chen;John J Thwaites - 通讯作者:
John J Thwaites
Patrick Shipman的其他文献
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{{ truncateString('Patrick Shipman', 18)}}的其他基金
Topological Analysis of Pattern-Forming Systems
图案形成系统的拓扑分析
- 批准号:
1814941 - 财政年份:2018
- 资助金额:
$ 13.13万 - 项目类别:
Standard Grant
Automated, Secure Homotopy Continuation and Parameter Space Exploration
自动化、安全的同伦延拓和参数空间探索
- 批准号:
1719658 - 财政年份:2017
- 资助金额:
$ 13.13万 - 项目类别:
Standard Grant
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