权益分类	功能权益	普通用户	{{item.name}}会员
{{category.name}}	{{benefitItem.name}}

Dexterous Fiber Optic Tweezers for Bio-Particle Manipulation and Force Sensing

用于生物粒子操纵和力传感的灵巧光纤镊子

基本信息

批准号：
1031331
负责人：
Miao Yu
金额：
$ 20万
依托单位：
University of Maryland, College Park
依托单位国家：
美国
项目类别：
Standard Grant
财政年份：
2010
资助国家：
美国
起止时间：
2010-08-15 至 2014-07-31
项目状态：
已结题

来源：
https://www.nsf.gov/awardsearch/showAward?AWD_ID=1031331&HistoricalAwards=false
关键词：
Dexterous Fiber Optic Tweezers Bio

项目摘要

Abstract1031331Miao YuUniversity of MarylandThe objective of this research project is to develop a dexterous dual fiber tweezers system with greatly enhanced flexibility, functionality, and efficiency. Through this research a fundamental understanding of such a system for manipulation and sensing of micro/nano sized particles will be achieved through a combination of thorough analytical, numerical, and experimental studies. The novel fiber optical tweezers equipped with surface plasmonic lens will significantly enhance the trapping efficiency compared with conventional fiber tweezers. Furthermore, by taking advantage of the advanced fiber optic modulation techniques, high speed and high resolution dynamical trapping position control will be enabled in the novel fiber optical tweezers. This effort is expected to not only enrich the fields of sensors, actuators, and biophotonics, but also pave the way for developing innovative tools for the study of biological systems, and shed further light on pathological mechanisms and disease diagnosis.The learning experience of undergraduate and graduate students will be enriched through an inter-disciplinary curriculum. The interests of K-12 students in science and engineering will be stimulated by involving them in multi-disciplinary research activities at the University of Maryland. Participation of underrepresented groups will be broadened through educational activities in the Center for Minorities in Science and Engineering.

苗宇马里兰大学本研究项目的目标是开发一种灵巧的双光纤镊子系统，该系统具有极大的灵活性、功能性和效率。通过这项研究，这样一个系统的操作和传感的微/纳米尺寸的颗粒的基本理解将通过彻底的分析，数值和实验研究的结合来实现。与传统的光纤光镊相比，采用表面等离子体透镜的新型光纤光镊将显著提高光镊的捕获效率。此外，通过利用先进的光纤调制技术，高速和高分辨率的动态捕获位置控制将在新的光纤光镊。这一努力不仅将丰富传感器、致动器和生物光子学领域，还将为开发用于生物系统研究的创新工具铺平道路，并进一步阐明病理机制和疾病诊断。通过跨学科课程，将丰富本科生和研究生的学习经验。K-12学生对科学和工程的兴趣将通过让他们参与马里兰州大学的多学科研究活动来激发。将通过少数民族科学和工程中心的教育活动扩大代表性不足群体的参与。