Partial Support for U.S. Participation in Workshop "Unlocking and Developing Collections for Genomic Research"

部分支持美国参与“解锁和开发基因组研究馆藏”研讨会

• 批准号: 1036865
• 负责人: Oliver Ryder
• 金额: $ 2.37万
• 依托单位: Zoological Society of San Diego
• 依托单位国家: 美国
• 项目类别: Standard Grant
• 财政年份: 2010
• 资助国家: 美国
• 起止时间: 2010-06-01 至 2011-05-31
• 项目状态: 已结题
• 来源: https://www.nsf.gov/awardsearch/showAward?AWD_ID=1036865&HistoricalAwards=false
• 关键词: Partial; Support; U.S.; Participation; Workshop

Partial Support for U.S. Participation in Workshop "Unlocking andDeveloping Collections for Genomic Research"Oliver RyderZoological Society of San DiegoAbstractThe tremendous advances being made in DNA sequencing technology now make it possible to generate and analyze extensive genomic information from extinct organisms and species on the brink of extinction, thereby providing a remarkable opportunity to use genomic sequences to study the extinction process. The results of recent studies that incorporate advancements in genome sequencing technology and methods to extract sufficient amounts of serviceable DNA are expanding the contributions of paleogenomic studies to the field of paleontology. The ability and to capture genetic information from animals and plants on the brink of extinction and to retrospectively analyze genetic attributes of extinct animals provides a new source of information applicable to evaluating the impacts of changing environments, including the impacts of newly emerging diseases and climate alterations on the persistence or decline of species over tens of thousands of years. The technological developments in DNA sequencing technology that are crucial to the developing field of paleogenomics and the genomics of extinction focus attention on the crucial importance of collections of samples useful for these studies. Collections of frozen specimens and Museum collections will provide vital samples to study changes taking place over time in changing environments. In order to provide a perspective for the utilization of museum collections, including collections of frozen biomaterials and DNA specimens, convening of scientific workshops provides a forum for discussion of preservation methods and development of collaborative studies. This proposal facilitates the participation of six U.S.-based scientists who are experts in this newly-emerging field, to participate in a workshop entitled ?Unlocking and Developing Collections for Genomic Research? to be held on June 11, 2010, at the Natural History Museum in London, and an accompanying Linnaean Society Meeting the preceding day entitled ?Sequencing the Red and the Dead?. Their attendance at this meeting is important for U.S. scientists to maintain a competitive advantage in this newly emerging field of investigation.

圣地亚哥动物学会奥利弗莱德摘要DNA测序技术的巨大进步使我们有可能从已灭绝的生物和濒临灭绝的物种中产生和分析大量的基因组信息，从而为利用基因组序列研究灭绝过程提供了一个难得的机会。最近的研究结果，包括基因组测序技术和方法的进步，以提取足够数量的有用的DNA正在扩大古基因组学研究的古生物学领域的贡献。从濒临灭绝的动物和植物中捕获遗传信息并回顾性分析灭绝动物的遗传属性的能力提供了一个新的信息来源，可用于评估不断变化的环境的影响，包括新出现的疾病和气候变化对物种在数万年内持续存在或衰退的影响。DNA测序技术的发展对古基因组学和灭绝基因组学的发展至关重要，这使得人们关注收集对这些研究有用的样本的至关重要性。冷冻标本和博物馆藏品的收集将为研究在不断变化的环境中随着时间的推移而发生的变化提供重要样本。为了提供利用博物馆收藏品的前景，包括冷冻生物材料和DNA标本的收藏品，召开科学讲习班为讨论保存方法和开展合作研究提供了一个论坛。 这一提议有助于六个美国-的科学家谁是专家在这个新兴的领域，参加一个研讨会，题为？解锁和开发基因组研究的集合？将于2010年6月11日在伦敦的自然历史博物馆举行，并在前一天举行了林奈学会会议，题为？《红色与死者》（Red and the Dead） 他们出席这次会议对于美国科学家在这一新兴研究领域保持竞争优势非常重要。