Collaborative Research: Integrated Primate Biomaterials and Information Resource

合作研究：综合灵长类生物材料和信息资源

• 批准号: 0094993
• 负责人: Oliver Ryder
• 金额: $ 203.38万
• 依托单位: Zoological Society of San Diego
• 依托单位国家: 美国
• 项目类别: Continuing Grant
• 财政年份: 2001
• 资助国家: 美国
• 起止时间: 2001-07-15 至 2007-06-30
• 项目状态: 已结题
• 来源: https://www.nsf.gov/awardsearch/showAward?AWD_ID=0094993&HistoricalAwards=false
• 关键词: Collaborative; Research; Integrated; Primate; Biomaterials

The conduct of advanced research involving biological materials from nonhuman primates requires open access to high quality, well documented samples. Until now, access has been opportunistic and quality control highly variable. This Infrastructure Award will establish an Integrated Primate Biomaterials and Information Resource that will be developed through a collaboration among Coriell Institute for Medical Research (Coriell), the International Species Information System (ISIS), Princeton University (PU), the San Diego Supercomputer Center (SDSC), and the Zoological Society of San Diego (ZSSD). The Resource will provide primate biomaterials such as DNA and cell lines for research that takes advantage of emerging genetic technologies and the human genome sequence to probe questions of human origins, primate phylogeny and biogeography, conservation, and human behavior and cognition. With policy and priorities guided by a broadly based Scientific Advisory Committee, the Resource collaboration includes institutions that bring expertise in biomaterials banking, bioinformatics, information access, and in primate conservation, behavior, and ecology. Resource priorities include high levels of quality control and wide accessibility to researchers who would not otherwise have access to necessary materials for research, conservation, and capacity-building. The collection will seek to provide a balance among diversity and depth of sampling combined with maximal associated information or other available with samples.

开展涉及非人类灵长类动物生物材料的高级研究需要开放获取高质量、记录良好的样本。到目前为止，准入一直是机会主义的，质量控制也是高度可变的。该基础设施奖将建立一个综合灵长类生物材料和信息资源，该资源将通过科里埃尔医学研究所（科里埃尔）、国际物种信息系统（ISIS）、普林斯顿大学（PU）、圣地亚哥超级计算机中心（SDSC）和圣地亚哥动物学会（ZSSD）之间的合作开发。该资源将提供灵长类动物生物材料，如DNA和细胞系，用于利用新兴的遗传技术和人类基因组序列来探索人类起源、灵长类动物系统发育和生物地理学、保护以及人类行为和认知等问题。在一个基础广泛的科学咨询委员会的政策和优先事项指导下，资源合作包括在生物材料银行、生物信息学、信息获取以及灵长类动物保护、行为和生态学方面提供专业知识的机构。资源优先事项包括高水平的质量控制和对研究人员的广泛获取，否则他们将无法获得研究、保护和能力建设所需的材料。收集将寻求在多样性和抽样深度之间提供平衡，并结合最大的相关信息或其他可获得的样本。