MRI: Acquisition of Accessories to Upgrade A Confocal Microscope Used for Research and Teaching at Wake Forest University

该主要研究仪器奖为维克森林大学的蔡司LSM 710共聚焦显微镜的系统升级提供资金。该仪器使教师、博士后、研究生和本科生能够研究和发表关于大脑可塑性的重要发现；植物发育的激素调控；果蝇的应激反应系统、基因表达和蛋白定位；DNA修复、蛋白质复合物形成、蛋白质氧化和翻译后修饰的机制。所要求的附件允许活细胞，动态和多标签实验，并提供更多的教育机会。与WFU加强校园外联系的使命一致，LSCM也被区域调查人员用于研究和教育，并在推广研讨会期间使用。这些研究和教学工作的成果将通过摘要和同行评议的出版物以及学生和教员积极参加专业会议而广泛传播。

This Major Research Instrumentation award funds the acquisition of system upgrades for a Zeiss LSM 710 confocal microscope at Wake Forest University. The instrumentation enables faculty, postdoctoral fellows, graduate students, and undergraduates to study and publish important findings on brain plasticity; hormonal regulation of plant development; stress response systems, gene expression, and protein localization in Drosophila; mechanisms of DNA repair, protein complex formation, protein oxidation, and posttranslational modification. The requested accessories permit live-cell, dynamic, and multi-label experiments and enable more educational opportunities. Consistent with WFU's mission to strengthen connections beyond campus, the LSCM is also used by regional investigators for research and education, and is utilized during outreach workshops. The results of these research and teaching efforts will be broadly disseminated through abstracts and peer reviewed publications, as well as by active participation of students and faculty at professional meetings.