MRI: Acquisition of a SELDI ProteinChip Reader

MRI：购买 SELDI ProteinChip Reader

• 批准号: 1039913
• 负责人: Pamela Lloyd
• 金额: $ 17.81万
• 依托单位: Oklahoma State University
• 依托单位国家: 美国
• 项目类别: Standard Grant
• 财政年份: 2010
• 资助国家: 美国
• 起止时间: 2010-11-01 至 2014-10-31
• 项目状态: 已结题
• 来源: https://www.nsf.gov/awardsearch/showAward?AWD_ID=1039913&HistoricalAwards=false
• 关键词: MRI; Acquisition; SELDI; ProteinChip; Reader

1039913YinThe College of Engineering at Oklahoma State University (OSU)recently initiated a joint program in Biomedical Engineering. Faculty members from the College of Engineering and Physiological Sciences have been involved in this new program. There has been a significant increase in research activities and collaborations among these faculty members, in the areas of biomechanics, biomaterials, bioelectricity, bioinformatics and bio-nano technology. Many research projects conducted by these faculty members involve protein-protein interactions and biomarkers studies. The surface-enhanced laser desorption/ionization (SELDI) ProteinChip reader is a rapid and high throughput system to study proteomics, protein interactions and enzymatic kinetic reactions. This technology has a high repeatability and only requires minimum sample volumes, which is a significant advantage for many low-yield biological systems. The ProteinChip reader can achieve ample information that would be otherwise undetectable from other measurement techniques. The ProteinChip technology will contribute significantly to the developing biomedical research in proteomics and biomarker studies. A SELDI ProteinChip reader will provide researchers, not only from OSU, but also those from nearby research institutes, a powerful new tool to broaden their research capabilities and to advance their research in proteomics and biomarker studies significantly.

俄克拉荷马州州立大学（OSU）的工程学院最近发起了一个生物医学工程的联合项目。来自工程和生理科学学院的教师参与了这个新项目。这些教师在生物力学，生物材料，生物电，生物信息学和生物纳米技术领域的研究活动和合作显着增加。这些教师进行的许多研究项目涉及蛋白质-蛋白质相互作用和生物标志物研究。表面增强激光解吸/电离（SELDI）蛋白质芯片阅读器是一种快速，高通量的系统，用于研究蛋白质组学，蛋白质相互作用和酶动力学反应。该技术具有高重复性，仅需要最小的样品体积，这对于许多低产生物系统来说是一个显著的优势。ProteinChip阅读器可以获得其他测量技术无法检测到的丰富信息。蛋白质芯片技术将为蛋白质组学和生物标志物研究的发展做出重要贡献。SELDI蛋白质芯片阅读器将为研究人员提供一个强大的新工具，不仅来自俄勒冈州立大学，而且来自附近的研究机构，以扩大他们的研究能力，并大大推进他们在蛋白质组学和生物标志物研究方面的研究。