Storable, Thermally Activated Chemiluminescent and Fluorescent Dyes

大分子，超分子和纳米化学（MSN）计划支持圣母大学的布拉德利史密斯教授研究可在零度下储存的荧光和荧光染料，然后通过简单地加热到体温来发射可见光或近红外光。该研究计划建立在最近发现的方酸轮烷内过氧化物的基础上，方酸轮烷内过氧化物是一种互锁的高能分子，具有独特的发光能力，无需化学或电刺激。研究目的是提高对产生化学发光的化学过程的基本理解，并利用新知识设计和制备具有优异发光性能的染料。这项工作可能使一系列新的生物技术和纳米技术的应用，采用自发光染料增强检测。研究型学生的核心训练是有机化学和光化学，重点是化学结构，合成和反应机理。更广泛的影响是通过与一组研究创业的科学商业学生的半正式互动来增强的。

The Macromolecular, Supramolecular and Nanochemistry (MSN) Program supports Professor Bradley Smith of the University of Notre Dame to study chemiluminescent and fluorescent dyes that can be stored at zero degrees and then made to emit visible or near-infrared light by simply warming to body temperature. The research plan builds on the recent discovery of squaraine rotaxane endoperoxides, interlocked high energy molecules with a unique ability to emit light without chemical or electrical stimulus. The research objective is to improve fundamental understanding of the chemical process that produces the chemiluminescence and to use the new knowledge to design and prepare dyes with outstanding emission properties. The work may enable a range of new biotechnology and nanotechnology applications that employ self-illuminating dyes for enhanced detection. The core training of research students is in organic chemistry and photochemistry with an emphasis on chemical structure, synthesis, and reaction mechanism. The broader impact is enhanced by a semi-formal interaction with a separate group of science business students who study entrepreneurship.