REU Site: Research Experience for Undergraduates in Chemistry and Biochemistry

该奖项由数学和物理科学理事会化学部（CHE）和生物科学理事会生物基础设施部（DBI）颁发，支持由加州州立大学洛杉矶分校Scott Nickolaisen领导的本科生研究经验（REU）项目。该网站支持的研究项目涉及化学的许多领域，但也有许多生物化学界面的项目。本科生将主要从缺乏基础设施来支持本科生研究的机构中招募，包括来自代表性不足群体的学生，特别强调洛杉矶盆地的社区大学生。该网站每年夏天将为10名学生提供为期10周的培训。(1)磁共振技术在生物相关大分子物理化学性质研究中的应用与发展；(2)环境污染物凝聚态光化学反应的研究；(3)饮食因素如何调控高密度脂蛋白代谢的研究；(4)磷酸烯醇丙酮酸羧化酶的变构活化位点研究；(5)非球对称树状大分子的制备，具有新的、工程的特征，如峡谷、裂缝和口袋；(6)较大（超过两个碳）烷基过氧自由基与其他大气成分的反应动力学研究。除了在夏季进行研究外，参加该计划的学生还将参加一些专业发展活动，包括负责任的研究行为、实验室安全和科学交流方面的培训。作为培训的一部分，年轻科学家需要接触现代研究方法和工具。这个REU网站旨在为没有重要研究经验的学生提供一个机会，在这个以本科生为主的机构中，与专门的教师导师一起进行化学科学方面的前沿研究。在这里参与研究的不同学生群体将为在化学科学、研究生院的进一步学习以及最终作为国家技术劳动力的一部分就业做好充分准备。

This award from the Division of Chemistry (CHE) in the Mathematical and Physical Sciences Directorate and the Division of Biological Infrastructure (DBI) in the Biological Sciences Directorate supports a Research Experience for Undergraduates (REU) site led by Scott Nickolaisen at California State University - Los Angeles. The research projects supported in this site are in a number of areas of chemistry, but with a number of projects at the Biology-Chemistry interface. Undergraduates will be recruited to this site primarily from institutions that lack infrastructure to support undergraduate research, including students from underrepresented groups, with a particular emphasis on community college students in the Los Angeles basin. The site will support ten students per summer in a ten week program. A sample of the projects that undergraduates will work on include: (1) the development and application of magnetic resonance techniques for the study of the physicochemical properties of biologically related macromolecule; (2) the study of the photochemical reactions of environmental pollutants in condensed phases; (3) the study of how dietary factors regulate the metabolism of high density lipoproteins; (4) the study of the allosteric activation sites of the enzyme phosphoenolpyruvate carboxylase; (5) the preparation of non-spherically symmetric dendrimers with novel, engineered features such as canyons, clefts, and pockets and (6) the study of the reaction kinetics of larger (more than two carbons) alkyl peroxy radicals with other atmospheric constituents. In addition to conducting research during the summer, the students participating in this program will participate in a number of professional development activities, including training on the responsible conduct of research, laboratory safety, and scientific communication.Young scientists need exposure to modern research methods and tools as part of their training. This REU site aims to provide students without significant research experience a chance to conduct cutting-edge research in the chemical sciences with dedicated faculty mentors at this predominantly undergraduate institution. The diverse student cohort participating in research at this site will be well-prepared for further study in the chemical sciences, graduate school, and eventual employment as part of the country's technical workforce.