Center for Pharmaceutical Development

药物开发中心

• 批准号: 1063879
• 负责人: Eric Munson
• 金额: $ 27.5万
• 依托单位: University of Kentucky Research Foundation
• 依托单位国家: 美国
• 项目类别: Continuing Grant
• 财政年份: 2010
• 资助国家: 美国
• 起止时间: 2010-05-18 至 2016-01-31
• 项目状态: 已结题
• 来源: https://www.nsf.gov/awardsearch/showAward?AWD_ID=1063879&HistoricalAwards=false
• 关键词: Center; Pharmaceutical; Development

0968003 Georgia Tech; Andy Bommarius 0968972 University of Kansas; Eric Munson The purpose of this proposal is to start a new I/UCRC "Pharmaceutical Manufacturing and Formulation" (CPMF) with a focus on addressing current challenges in the pharmaceutical industry, and developing solutions towards more selective and robust manufacturing processes, more stable formulations, and better characterized and consistent products. The lead institution of the proposed Center is Georgia Tech with a site location at the University of Kansas. CPMF proposes to explore areas important to pharmaceutical manufacturing and improved formulations for pharmaceuticals. The Center plans to develop methods and technologies that will produce better pharmaceuticals, make them last longer, be more effective, and safer. By combining the efforts of Georgia Tech, Duquesne University and the University of Kansas, the PIs have proposed a number of potentially important projects that could significantly advance the applied knowledge necessary to make better pharmaceuticals. CPMF will allow pharmaceutical companies a lower cost approach to advancing risky research in a cooperative manner such that important manufacturing needs and innovations can be pursued with shared risk and mutual gain. CPMF has assembled a very strong group of researchers who are well-qualified to perform the research outlined in the proposal. The proposed Center will promote the rapid development of safe and efficacious drugs and drug formulations, and will identify potential problems with proposed drug formulations, with the potential of improving or even saving human lives. The Center plans to involve graduate students and post-doctoral associates in performing and presenting their research, thereby creating an opportunity for them to interact with counterparts from pharmaceutical and medical areas. Plans for dissemination of results are well thought out and audiences are appropriate. The proposed Center also plans to put emphasis on recruiting under-represented groups.

0968003佐治亚理工学院；Andy Bommarius 0968972堪萨斯大学；该提案的目的是启动一个新的I/UCRC“药物制造和配方”（CPMF），重点关注制药行业当前的挑战，并开发解决方案，以实现更具选择性和健壮的制造工艺，更稳定的配方，更好地表征和一致的产品。该中心的主要机构是乔治亚理工学院，地点位于堪萨斯大学。CPMF建议探索药品生产和改进药品配方的重要领域。该中心计划开发方法和技术，以生产更好的药物，使其持续时间更长，更有效，更安全。通过联合佐治亚理工学院、杜肯大学和堪萨斯大学的努力，这些私人投资机构提出了许多潜在的重要项目，这些项目可以显著推进制造更好药物所必需的应用知识。CPMF将允许制药公司以更低的成本以合作的方式推进高风险的研究，这样重要的生产需求和创新就可以在风险共担和互惠互利的情况下进行。CPMF已经组建了一个非常强大的研究小组，他们非常有资格进行提案中概述的研究。拟建中心将促进安全有效的药物和制剂的快速发展，并将识别拟建制剂的潜在问题，这些问题具有改善甚至挽救人类生命的潜力。该中心计划让研究生和博士后参与他们的研究，从而为他们创造一个与制药和医疗领域的同行互动的机会。传播结果的计划是经过深思熟虑的，受众是适当的。该中心还计划把重点放在招募代表性不足的群体上。