New phylogenetic approaches for understanding evolution at the genome scale

用于理解基因组规模进化的新系统发育方法

• 批准号: DP160104173
• 负责人: Prof Simon Ho
• 金额: $ 25.15万
• 依托单位: The University of Sydney
• 依托单位国家: 澳大利亚
• 项目类别: Discovery Projects
• 财政年份: 2016
• 资助国家: 澳大利亚
• 起止时间: 2016-01-01 至 2019-12-31
• 项目状态: 已结题
• 来源: https://dataportal.arc.gov.au/RGS/Web/Grants/DP160104173
• 关键词: New; phylogenetic; approaches; understanding; evolution

This project aims to use genome data to improve our understanding of the evolutionary process, including the forces that shape evolution on a whole-genome scale. The project plans to create a curated database of genome sequences and a comprehensive framework for evolutionary analyses of genomes. The new approach is designed to be used to analyse patterns of evolutionary rate variation to identify the key features of genome evolution. In addition, the development of a genome-scale approach to molecular dating will improve estimates of the timescale of the Tree of Life. This project is expected to yield useful insights into molecular evolution and to provide a valuable guide for future evolutionary analyses of genomes.

该项目旨在利用基因组数据来提高我们对进化过程的理解，包括在全基因组规模上塑造进化的力量。该项目计划创建一个基因组序列数据库和一个基因组进化分析的综合框架。这种新方法被设计用来分析进化速率变化的模式，以确定基因组进化的关键特征。此外，基因组尺度的分子定年方法的发展将改善对生命之树时间尺度的估计。该项目有望为分子进化提供有用的见解，并为未来的基因组进化分析提供有价值的指导。