GARDE: An Interdisciplinary Approach to Accommodate Fine Motor Control Disorders

GARDE：治疗精细运动控制障碍的跨学科方法

• 批准号: 1133992
• 负责人: Rifat Sipahi
• 金额: $ 27.07万
• 依托单位: Northeastern University
• 依托单位国家: 美国
• 项目类别: Standard Grant
• 财政年份: 2011
• 资助国家: 美国
• 起止时间: 2011-10-01 至 2016-09-30
• 项目状态: 已结题
• 来源: https://www.nsf.gov/awardsearch/showAward?AWD_ID=1133992&HistoricalAwards=false
• 关键词: GARDE; Interdisciplinary; Approach; Accommodate; Fine

PI: Sipahi, R.; Frank, S.; Gouldstone, A.; and Jaeger, B. K.Proposal Number: 1133992 Synopsis This GARDE proposal describes activities to investigate fundamental aspects of hand-pen-paper interaction during writing, with a movement disorder that causes undesired oscillation (tremors). Efforts will lead to strategies to accommodate such a disorder, and in return improve writing ability of those suffering from kinetic tremor - a type of impairment found in 10-12 million people in the US with Parkinson's Disease, Essential Tremor, and Dystonia. The novelty of our proposal is the interdisciplinary, engineering-based approach; we frame this problem in terms of the following questions: -Given a set of wrist vibrations, what are the pen grip/pen mechanics conditions that would cause "unintended penmanship" (i.e., pen slip on paper)? How can penmanship be improved actively or passively? To address this complex problem, we first frame writing ability in the context of human factors and performance metrics (PM) on end-users. The elderly target population will be established via collaboration with a neurologist at Boston Medical Center. We then build dynamic models of a pen being oscillated by the hand, under various conditions, and use a control theory approach to accommodate oscillations, on the pen. Finally, we will implement and construct these approaches into a "Smart Pen" that will be tested on an end-user population. Design refinements will also include 3D contact mechanics models of grip and friction, and undergraduate Senior Design team efforts in prototypes, using a series of sensors and actuators. Intellectual Merit This activity is important, in that beyond simply making a "better pen", it seeks to fully define the design space within which researchers can work to accommodate the effects of a movement disorder upon writing. The problem is tractable, as we have assembled experts in contact mechanics (CAREER awardee), controls, human factors and neurology. We believe this work could transform the field, as other researchers can access our modeling data and use guidelines to explore further therapeutic concepts. In addition, this work will promote the concept of "computational design." We have made every effort to make the thrusts correct, synergistic, relevant and within the scope of the devised program, and will leverage existing resources at NU (including startup grants) to purchase necessary equipment. Broader ImpactThe graduate assistant(s) in this program will be exposed to a highly interdisciplinary set of scientific studies, creating a well-rounded base, with strong societal perspective. The PI's and expected undergraduate participants represent a range of demographics, including support from NU?s minority programs. Specific dissemination activities are ambitious and pervasive, and will leverage the PIs' projects BELLA (Bringing Education and Lifelong Learning to Adults) through seminars and discussions directly to the elderly population. Undergraduate senior engineering students will use the design criteria to build actual prototype devices. The results, devices and dissemination will be highly enabling and empowering, particularly to the elderly, as it will provide them with a non-invasive means to maintain independence later in life. Other possible uses for this work include healthy subjects and/or tremor patients holding a cup filled with liquid, holding a utensil, manipulating a joystick, operating machinery, holding a sensitive device in precision surgery or in a vibratory environment.

PI：Sipahi，R.; Frank，S.; Gouldstone，A.;和Jaeger，B. K.提案编号：1133992概要本GARDE提案描述了研究书写过程中手-笔-纸相互作用的基本方面的活动，以及导致不希望的振荡（震颤）的运动障碍。努力将导致适应这种疾病的策略，并作为回报提高那些患有运动性震颤的人的写作能力-在美国有10-12百万帕金森病，原发性震颤和肌张力障碍的人中发现的一种障碍。我们的建议的新奇是跨学科的，基于工程的方法;我们根据以下问题来构建这个问题：-给定一组手腕振动，什么是会导致“意外笔迹”的握笔/笔力学条件（即，纸上的笔误）？如何主动或被动地提高书法水平？为了解决这个复杂的问题，我们首先在最终用户的人为因素和性能指标（PM）的背景下构建写作能力。老年目标人群将通过与波士顿医疗中心的神经科医生合作确定。然后，我们建立动态模型的笔被振荡的手，在各种条件下，并使用控制理论的方法来适应振荡，笔。最后，我们将实施和构建这些方法到一个“智能笔”，将在最终用户群体进行测试。设计改进还将包括抓地力和摩擦力的3D接触力学模型，以及本科高级设计团队使用一系列传感器和执行器在原型中的努力。智力价值这项活动是重要的，因为除了简单地制造一个“更好的笔”，它试图充分定义设计空间，研究人员可以在其中工作，以适应运动障碍对写作的影响。这个问题是容易处理的，因为我们聚集了接触力学（CAREER获奖者），控制，人为因素和神经学方面的专家。我们相信这项工作可以改变这个领域，因为其他研究人员可以访问我们的建模数据并使用指南来探索进一步的治疗概念。此外，这项工作将促进“计算设计”的概念。“我们已尽一切努力，使推力正确，协同，相关和范围内的设计方案，并将利用现有资源在NU（包括启动赠款）购买必要的设备。更广泛的影响本计划的研究生助理将接触到一套高度跨学科的科学研究，创造一个全面的基础，具有强大的社会视角。PI的和预期的本科生参与者代表了一系列的人口统计数据，包括从NU？少数民族节目。具体的传播活动雄心勃勃，而且无处不在，将通过直接面向老年人口的研讨会和讨论，利用公共机构的“向成人提供教育和终身学习”项目。本科高年级工程专业的学生将使用设计标准来构建实际的原型设备。其成果、设备和传播将具有很强的能力和赋权作用，特别是对老年人，因为它将为他们提供一种非侵入性的手段，使他们在以后的生活中保持独立。这项工作的其他可能用途包括健康受试者和/或震颤患者手持装满液体的杯子，手持器具，操纵操纵杆，操作机器，在精密手术或振动环境中手持敏感设备。