Gametogenesis-related small non-coding RNAs and Argonaute proteins in Arabidopsis (B05)

拟南芥配子发生相关小非编码 RNA 和 Argonaute 蛋白 (B05)

• 批准号: 202938851
• 金额: --
• 依托单位: Lehrstuhl für Zellbiologie und Pflanzenbiochemie
• 依托单位国家: 德国
• 项目类别: Collaborative Research Centres
• 财政年份: 2011
• 资助国家: 德国
• 起止时间: 2010-12-31 至 2022-12-31
• 项目状态: 已结题
• 来源: https://gepris.dfg.de/gepris/projekt/202938851?language=en
• 关键词: Gametogenesis; related; small; non; coding

Small RNAs and Argonautes are central to gene regulation but analysis of these ribonucleoprotein (RNP) complexes in the flowering plant egg cell remains challenging because it is deeply buried inside the ovary. Project B5 aims to uncover small RNA profiles and RNP complexes of Arabidopsis egg cells and to investigate whether and how miRNAs in the egg cell impact cell specification, fertilization or embryogenesis. Furthermore, project B5 aims to elucidate the molecular mechanism(s) of cell-to-cell small RNA transfer in the microenvironment of the female gametophyte for intercellular communication.

小RNA和精氨酸是基因调控的中心，但对开花植物卵细胞中这些核糖核蛋白(RNP)复合体的分析仍然具有挑战性，因为它深深地埋藏在卵巢中。B5项目旨在揭示拟南芥卵细胞的小RNA图谱和RNP复合体，并研究卵细胞中的miRNAs是否以及如何影响细胞规格、受精或胚胎发育。此外，B5项目旨在阐明在雌配子体的微环境中进行细胞间通讯的细胞间小RNA转移的分子机制(S)。