Patient-specific computational tools for evaluating functional performance of total knee replacements in vivo

用于评估全膝关节置换体内功能性能的患者专用计算工具

• 批准号: LP0990369
• 负责人: Prof Marcus Pandy
• 金额: $ 25.34万
• 依托单位: The University of Melbourne
• 依托单位国家: 澳大利亚
• 项目类别: Linkage Projects
• 财政年份: 2009
• 资助国家: 澳大利亚
• 起止时间: 2009-12-02 至 2015-12-31
• 项目状态: 已结题
• 来源: https://dataportal.arc.gov.au/RGS/Web/Grants/LP0990369
• 关键词: Patient; specific; computational; tools; evaluating

Knee replacement surgery is the established treatment for end-stage osteoarthritis. This proposal addresses one of the most fundamental questions related to knee replacement surgery: Why do total knee replacements fail? High-fidelity, patient-specific computer simulations of walking can help to answer this question and, in so doing, can improve the functional performance and longevity of current knee implant designs. Realistic computer simulations of human movement also can play a pivotal role in healthcare through patient rehabilitation; in sports, through the development of personalized training programs for elite athletes; and in entertainment, through the creation of video games and animated films.

膝关节置换手术是终末期骨关节炎的既定治疗方法。该提案解决了与膝关节置换手术相关的最基本问题之一：为什么全膝关节置换术失败？高保真度，患者特定的计算机模拟行走可以帮助回答这个问题，这样做，可以提高当前膝关节植入物设计的功能性能和寿命。人体运动的逼真计算机模拟也可以通过患者康复在医疗保健中发挥关键作用;在体育运动中，通过为精英运动员开发个性化训练计划;以及在娱乐中，通过创建视频游戏和动画电影。