Developing Patient-Specific Models of Whole Brain Networks in Depression to Examine the Network Effects of Focal Neurostimulation

开发抑郁症患者的全脑网络模型以检查局灶神经刺激的网络效应

• 批准号: 489876
• 负责人: Protzner Andrea B
• 金额: $ 68.27万
• 依托单位: University of Calgary
• 依托单位国家: 加拿大
• 项目类别: Operating Grants
• 财政年份: 2023
• 资助国家: 加拿大
• 起止时间: 2023-09-01 至 2028-09-01
• 项目状态: 未结题
• 来源: https://webapps.cihr-irsc.gc.ca/decisions/p/project_details.html?applId=489876&lang=en
• 关键词: Computational Methods; Eeg; Inter-Individual Differences; Major Depressive Disorder; Mri; Network Connectivity; Neural Networks; Transcranial Magnetic Stimulation; Treatment Resistant Depression

Up to 30% of people with severe depression do not respond to standard therapies. They can benefit from brain stimulation, which is thought to modulate brain circuits. Stimulation is most commonly applied through the skull non-invasively with repetitive tr

高达30%的严重抑郁症患者对标准治疗没有反应。他们可以受益于大脑刺激，这被认为是调节大脑回路。刺激最常通过颅骨施加，无创性，重复性刺激。