CAREER: Integrated Research and Education on Microscale Ferrohydrodynamic Manipulation

职业：微尺度铁流体动力操纵的综合研究和教育

• 批准号: 1150042
• 负责人: Leidong Mao
• 金额: $ 40万
• 依托单位: University of Georgia Research Foundation Inc
• 依托单位国家: 美国
• 项目类别: Standard Grant
• 财政年份: 2012
• 资助国家: 美国
• 起止时间: 2012-05-01 至 2018-04-30
• 项目状态: 已结题
• 来源: https://www.nsf.gov/awardsearch/showAward?AWD_ID=1150042&HistoricalAwards=false
• 关键词: CAREER; Integrated; Research; Education; Microscale

Objective: The objective of this program is to combine theoretical, numerical and experimental studies to investigate ferrofluid hydrodynamics and its applications in manipulating non-magnetic objects (such as molecules, particles, cells and droplets) at the micro-scale for lab-on-a-chip applications.Intellectual Merit: The intellectual merit is a multi-disciplinary research program that incorporates colloidal chemistry, magnetism and fluid mechanics, combining fundamental modeling and analysis with application-oriented experiments. It results in testable theoretical predictions and a physical understanding of ferrohydrodynamic manipulation of molecules and particles that enables practical and useful applications in microfluidic devices. A novel approach involving ferrofluids will be used to provide a magnetically uniform environment for molecules and cells, which can be transported with controlled speed and direction via external magnetic fields. Fast mixing of molecules and efficient manipulation of cells within ferrofluids will be enabled through this research.Broader Impact: The broader impacts are: (1) this program will not only advance the fundamental understanding of coupled nano-scale magnetic phenomena and fluid dynamics, but also produce a transformative magnetic manipulation platform that is applicable to a broad range of areas such as microfluidic biosensors, diagnostic chips, blood cleansing devices, and single cell studies; (2) this program will integrate research with lectures and laboratory assignments for undergraduate and graduate students, increase minority and female students? participations in science and engineering, and bring awareness of scientific concepts to K-12 students using ferrofluids through a ?Summer Institute? for K-12 teachers.

目的：本计画的目标是结合联合收割机的理论、数值与实验研究，探讨铁磁流体流体动力学及其在操控非磁性物体上的应用（如分子、颗粒、细胞和液滴），用于芯片实验室应用。知识优势：智力的优点是一个多学科的研究计划，结合胶体化学，磁学和流体力学，结合基础建模和分析与面向应用的实验。它导致可测试的理论预测和铁磁流体动力学操纵的分子和粒子，使实际和有用的应用在微流体装置的物理理解。一种涉及铁磁流体的新方法将用于为分子和细胞提供磁性均匀的环境，这些分子和细胞可以通过外部磁场以受控的速度和方向进行运输。通过这项研究，将能够在铁磁流体中快速混合分子和有效操纵细胞。更广泛的影响：更广泛的影响是：（1）该计划不仅将推进对耦合纳米尺度磁现象和流体动力学的基本理解，而且还将产生适用于微流体生物传感器，诊断芯片，血液净化设备和单细胞研究;（2）该计划将把研究与本科生和研究生的讲座和实验作业结合起来，增加少数民族和女性学生？参与科学和工程，并通过一个？暑期学校？K12教师