EAGER: Evaluating small sugars as recognition molecules for the detection of Abeta in Alzheimer's disease

EAGER：评估小糖作为识别分子以检测阿尔茨海默病中的 Abeta

• 批准号: 1151033
• 负责人: Michael Benton
• 金额: $ 2万
• 依托单位: Louisiana State University
• 依托单位国家: 美国
• 项目类别: Standard Grant
• 财政年份: 2011
• 资助国家: 美国
• 起止时间: 2011-08-15 至 2013-07-31
• 项目状态: 已结题
• 来源: https://www.nsf.gov/awardsearch/showAward?AWD_ID=1151033&HistoricalAwards=false
• 关键词: EAGER; Evaluating; small; sugars; recognition

1151033HenryThis NSF award by the Biosensing program supports the development of novel carbohydrate biorecognition molecules that could be used both for in vivo and in vitro detection of structure specific forms of beta amyloid, the primary protein component of senile plaques in Alzheimer's disease. The work will contribute to the development of new methods for diagnosing and following disease progression in Alzheimer's patients. The need for good quantitative clinical measures is needed for successful development of new drugs to treat this progressive neurological disease.

1151033亨利生物传感计划的NSF奖项支持开发新型碳水化合物生物识别分子，这些分子可用于体内和体外检测β淀粉样蛋白的结构特异性形式，β淀粉样蛋白是阿尔茨海默病中老年斑的主要蛋白质成分。 这项工作将有助于开发诊断和跟踪阿尔茨海默病患者疾病进展的新方法。 需要良好的定量临床措施，需要成功开发新药来治疗这种进行性神经系统疾病。