MRI: Acquisition of a State-of-the-Art Small Angle X-Ray Scattering (SAXS) Instrument for Research and Education

MRI：采购最先进的小角度 X 射线散射 (SAXS) 仪器用于研究和教育

• 批准号: 1228817
• 负责人: Mu-Ping Nieh
• 金额: $ 56.84万
• 依托单位: University of Connecticut
• 依托单位国家: 美国
• 项目类别: Standard Grant
• 财政年份: 2012
• 资助国家: 美国
• 起止时间: 2012-09-15 至 2015-08-31
• 项目状态: 已结题
• 来源: https://www.nsf.gov/awardsearch/showAward?AWD_ID=1228817&HistoricalAwards=false
• 关键词: MRI; Acquisition; State; Art; Small

This award to the University of Connecticut is for the acquisition of a versatile Small-angle X-ray Scattering (SAXS) instrument that can also be used for wide-angle and grazing-angle scattering measurements. SAXS is a powerful tool for the characterization of structures at length scales from a few to a few hundred nanometers. It provides information on the shape, size, molecular weight, polydispersity, and interparticle interactions of materials. This instrument will further ongoing research in polymer science, molecular biology, pharmaceutical science, nanomaterials, and energy research. It will be used to answers fundamental questions, such as: What is the ordering of inorganic templates and catalysts? How does the structure of various targeted drug carriers affect their function? What factors control the associations of bio-derived building blocks? And, how do structures form in molecular assemblies? The SAXS instrument will be housed in a shared user facility, which provides access to researchers across campus as well as local industry. It will enable research projects that improve health care, develop more efficient sources of energy, and produce materials with superior properties. The instrument will be used to train the next generation of scientists through hands-on research experiences for undergraduate students, graduate students, and post-docs, as well as classroom demonstrations in structural characterization courses.

该奖项授予康涅狄格大学是为了获得多功能小角度x射线散射（SAXS）仪器，该仪器也可用于广角和掠角散射测量。SAXS是表征从几到几百纳米长度尺度结构的有力工具。它提供了关于材料的形状、大小、分子量、多分散性和粒子间相互作用的信息。该仪器将进一步推进聚合物科学、分子生物学、制药科学、纳米材料和能源研究等领域的研究。它将用于回答一些基本问题，例如：无机模板和催化剂的排序是怎样的？各种靶向药物载体的结构如何影响它们的功能？哪些因素控制着生物衍生的构建块的关联？分子组合中的结构是如何形成的？SAXS仪器将被安置在一个共享的用户设施中，为校园和当地工业的研究人员提供访问权限。它将使研究项目能够改善医疗保健，开发更有效的能源，并生产具有优越性能的材料。该仪器将通过本科生、研究生和博士后的实践研究经验，以及结构表征课程的课堂演示，用于培养下一代科学家。