MRI: Acquisition of a State-of-the-Art Small Angle X-Ray Scattering (SAXS) Instrument for Research and Education
MRI: Acquisition of a State-of-the-Art Small Angle X-Ray Scattering (SAXS) Instrument for Research and Education
批准号:
1228817
负责人:
Mu-Ping Nieh
金额:
$56.84万
依托单位国家:
美国
项目类别:
Standard Grant
财政年份:
2012
资助国家:
美国
项目状态:
已结题
起止时间:
2012-09-15 至 2015-08-31
中文摘要
授予康涅狄格大学的这一奖项是为了获得一种多功能的小角X射线散射(SAXS)仪器,该仪器也可用于广角和掠角散射测量。 小角X射线散射是一个强大的工具,用于表征结构的长度尺度从几个到几百个纳米。 它提供了关于材料的形状、尺寸、分子量、多分散性和颗粒间相互作用的信息。 该仪器将进一步推动聚合物科学、分子生物学、制药科学、纳米材料和能源研究方面正在进行的研究。 它将被用来回答基本问题,如:什么是无机模板和催化剂的顺序? 各种靶向药物载体的结构如何影响其功能? 哪些因素控制着生物衍生的构建模块的关联? 分子组装中的结构是如何形成的?SAXS仪器将被安置在一个共享的用户设施中,该设施为整个校园以及当地行业的研究人员提供访问权限。 它将使研究项目能够改善医疗保健,开发更有效的能源,并生产具有上级性能的材料。该仪器将用于通过本科生,研究生和博士后的实践研究经验以及结构表征课程的课堂演示来培训下一代科学家。
英文摘要
This award to the University of Connecticut is for the acquisition of a versatile Small-angle X-ray Scattering (SAXS) instrument that can also be used for wide-angle and grazing-angle scattering measurements. SAXS is a powerful tool for the characterization of structures at length scales from a few to a few hundred nanometers. It provides information on the shape, size, molecular weight, polydispersity, and interparticle interactions of materials. This instrument will further ongoing research in polymer science, molecular biology, pharmaceutical science, nanomaterials, and energy research. It will be used to answers fundamental questions, such as: What is the ordering of inorganic templates and catalysts? How does the structure of various targeted drug carriers affect their function? What factors control the associations of bio-derived building blocks? And, how do structures form in molecular assemblies? The SAXS instrument will be housed in a shared user facility, which provides access to researchers across campus as well as local industry. It will enable research projects that improve health care, develop more efficient sources of energy, and produce materials with superior properties. The instrument will be used to train the next generation of scientists through hands-on research experiences for undergraduate students, graduate students, and post-docs, as well as classroom demonstrations in structural characterization courses.
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