Workshop: A roadmap for developing and implementing minimum nonomaterial characterization reporting requirements within regulatory ..., Summer/Fall 2012, Research Triangle Park, NC

摘要#1239092 Maynard本提案旨在为研讨会提供与会者差旅支持，以启动监管和开发社区内最低纳米材料表征报告要求的制定和实施。该研讨会是由国际生命科学研究所（ILSI）研究基金会风险科学创新和应用中心（RSIA）开发和领导的项目（NanoCharacter）的一部分。 尽管对工程纳米材料的环境和健康影响的研究越来越多，但在确保新兴材料和产品的安全性方面取得的进展仍然受到限制，因为已发表的研究中材料表征不佳，研究界采用的表征标准和准则很少。纳米特性项目正在制定一个框架和路线图，详细说明需要做些什么，通过鼓励在特定研究领域内采用特性一致性来提高纳米材料影响研究的质量和效用;就路线图在国际上、在各烟囱和各利益攸关方之间建立共识，建立一个多利益相关者小组，以监测和报告路线图的实施情况，并根据需要调整路线图，以促进采用一致的特征描述和报告。计划的研讨会将于2012年8月至10月在北卡罗来纳州三角研究园的国家环境健康科学研究所举行（确切日期取决于设施和参与者的可用性）。它将提供纳米字符项目？的指导委员会和专家小组，并设有一个论坛，与学术界、政府和监管机构的领导人接触，标准制定机构和主要出版社的编辑，以征求和考虑最有可能影响任何此类框架成功实施的人的意见。研讨会的成果将包括制定和实施最低限度纳米材料表征报告的框架和路线图要求.这将是一个独立的文件出版，并将在随后的几个月内由项目团队开发。拟议活动的知识价值：严格的，可重复的研究nanomerial-biologicalinteractions是关键依赖于相关的和一致的材料理化特性。同样，这一领域越来越多的研究的价值取决于公认的表征方法和程序。拟议的活动将大大加强在这一领域开展的研究的质量和价值。拟议的活动产生的更广泛的影响：利用工程纳米材料的产品的可持续和负责任的商业化取决于健全的风险评估。这一活动将进一步加强国家和国际两级进行这种评价的基础。

Abstract#1239092MaynardThis proposal is to provide participant travel support for a workshop to initiate the development and implementation of minimum nanomaterial characterization reporting requirements within regulatory and development communities. The workshop is part of a project (NanoCharacter)developed and led by the Center for Risk Science Innovation and Application (RSIA) at theInternational Life sciences Institute (ILSI) Research Foundation. Despite increasing research on the environmental and health impacts of engineered nanomaterials, progress in ensuring the safety of emerging materials and products remains limited by poormaterial characterization in published studies and minimal adoption of characterization standards and guidelines within the research community. The NanoCharacter project is developing a framework and roadmap detailing what needs to be done to improve the quality and utility of nanomaterial impact research through encouraging the adoption of characterization consistency within particularstudy domains; building consensus on the roadmap internationally, across stovepipes, and across stakeholders, and establishing a multi-stakeholder panel to monitor and report out the implementation of the roadmap and to adapt the roadmap as necessary to facilitate adoption of consistent characterization and reporting.The planned workshop will be held between August and October 2012 at the National Institute for Environmental Health Sciences in Research Triangle Park, NC (the precise dates are dependent on facility and participant availability). It will provide the NanoCharacter project?s Steering Committee and Expert Panel with a forum to engage with leaders from academia, government and regulatory agencies, standard setting bodies and editors of the key publishing houses in order to solicit and consider input from those who are most likely to affect the successful implementation of any such framework.Outputs of the workshop will include a framework and roadmap for developing and implementing minimum nanomaterial characterization reporting requirements. This will be a standalone document for publication and will be developed by project teams over the subsequent months.Intellectual merit of the proposed activity: Rigorous, reproducible research into nanomaterial-biologicalinteractions is critically dependent on relevant and consistent materials physicochemical characterization. Likewise, the value of a growing body of research in this area depends on accepted characterization approaches and procedures. The proposed activity will strengthen significantly the quality and value of research undertaken in this domain.Broader impacts resulting from the proposed activity: Sustainable and responsible commercialization of products that utilize engineered nanomaterials depends on sound risk evaluation. This activity will further strengthen the basis for such evaluations, nationally and internationally.