SBIR Phase I: Serendipitous Search System Using Lateral Analogy to Match Potential Solutions to Unmet Needs:Feasibility Study Based on Screening Approved Drugs for Potential Repur

这个小企业创新研究（SBIR）第一阶段项目的重点是通过在其他未连接的知识网络中发现横向连接来开发构思和创新的新方法。在人类知识和活动的许多领域，一个共同的特点是，信息内容正在以这样一种速度扩展，以至于越来越难以找到与搜索解决方案相关的结果。另一个问题是，即使是高质量的材料也在以这样的速度扩展，以至于大多数学科都在迅速形成分支学科。随着各领域在知识总量的顶层不断扩展，并通过分裂成越来越多的子领域而在更细粒度的层面上扩展，每个子领域都可能发展自己的期刊，会议甚至术语，外人无法理解。现在已经不可能跟上潮流了然而，许多创造力发生了，而且确实是世界上的许多人？人类的伟大发明，恰恰发生在不同领域的交叉点上。这个第一阶段项目的中心目标是确定一个可解析的本体的效用，通过连接不同的知识领域来支持构思和创新。 该项目更广泛的影响/商业潜力跨越多个领域和市场，包括但不限于制药、医疗器械、材料科学、半导体设备、化学加工、法律的发现、专利分析和金融分析。在每一个领域，不同知识领域的“孤岛”现象往往有所增加，它们之间的访问和语言障碍也在增加，这给学术界和工业界带来了明显的挑战。随着这种情况的发展，需要有更好的方法来组织、翻译和向用户提供信息，并找到解决用户问题（他们的“未满足的需要”）的办法。我们需要的是一个探索系统，它为搜索者提供了一个强大的偶然因素，最大可能的结果来自一个多样化的、意想不到的和潜在的挑衅性来源。这将打破孤岛，为不同学科之间的知识转移提供快速、相关的手段，促进对潜在解决方案的认识从一个领域迅速传播到另一个领域，促进跨学科创新。最初的客户重点将是在研发活动中投入大量资金且内部知识孤岛可能性很高的特定企业客户，如制药公司。

This Small Business Innovation Research (SBIR) Phase I project is focused on the development of novel methods for ideation and innovation through the discovery of lateral connections in otherwise unconnected knowledge networks. In many fields of human knowledge and activity, a common feature is that information content is expanding at such a rate that finding relevant results to searches for solutions is becoming increasingly difficult. A further problem is that even the high quality material is expanding at such a rate that most disciplines are rapidly forming sub-disciplines. As fields continue to both expand both at the top levels in terms of overall amount of knowledge, and to expand at the more granular levels by fragmentation into ever more numerous subfields, each of which may develop its own journals, conferences and even terminology, impenetrable to the outsider. It's becoming impossible to stay current. Yet much of creativity occurs, and indeed a great many of the world?s great inventions have occurred, precisely at the intersections between different fields. The central objective of this Phase I project will be to determine the utility of a parsable ontology for supporting ideation and innovation by connecting diverse knowledge domains. The broader impact/commercial potential of this project spans multiple fields and markets, including but not limited to pharmaceuticals, medical devices, materials science, semiconductor devices, chemical processing, legal discovery, patent analyses, and financial analytics. In each of these fields, there is often an increase in 'silo-ing' of different knowledge domains, with the development of access and language barriers in between them, presenting clear challenges to academia and industry. As this situation worsens, there is need of ever better ways to organize, translate and present information to users, and to find solutions to users' problems (their 'unmet needs'). What is needed, and not yet offered by any competitor, is an exploration system giving searchers a strong serendipitous element with a maximum likelihood of results having come from a diverse, unexpected, and potentially provocative source. This will break down silos by providing a rapid, relevant means for knowledge-transfer between different disciplines to facilitate the ready spread of awareness of a potential solution from one field to another, fostering interdisciplinary innovation. The initial customer focus will be on particular corporate clients with a heavy investment in R&D activities and a high probability of internal silo-ing of knowledge, such as pharmaceutical companies.