RUI: The nervous system of the Nine-banded Armadillo (Dasypus novemcinctus)

RUI:九带犰狳(Dasypus novemcinctus)的神经系统

基本信息

  • 批准号:
    1257891
  • 负责人:
  • 金额:
    $ 32.05万
  • 依托单位:
  • 依托单位国家:
    美国
  • 项目类别:
    Standard Grant
  • 财政年份:
    2013
  • 资助国家:
    美国
  • 起止时间:
    2013-09-15 至 2017-06-30
  • 项目状态:
    已结题

项目摘要

Understanding how brains become organized into specialized regions (touch, motor, vision, etc.) is essential to understanding how brains develop, as well as how they might be impacted and potentially repaired following developmental disorders or injuries. An effective strategy for acquiring a better understanding of brain organization involves examining mammals that possess unique body structures and behaviors. The goal of these studies is to characterize the organization and function of brain regions in the nine-banded armadillo (Dasypus novemcinctus), utilizing anatomical and electrophysiological recording methods. This project will reveal how mammalian nervous systems process specialized sensory inputs. Armadillos are covered in bony plates and are highly dependent upon their sense of hearing. These traits are expected to impact the brain regions responsible for touch, movement and hearing; understanding this relationship will shed light on analogous systems in other mammals such as humans. In addition to possessing sensory specializations, armadillos also uniquely give birth to identical quadruplets (basically clones), setting the stage for related neurodevelopmental studies with identical littermates for comparison, an ideal experimental situation unattainable with any other mammalian developmental model. These studies will take place at the University of Central Arkansas and involve training undergraduate and master's students, many of whom are first generation college students, in cutting edge neurobiology research methods. Participating students will engage in the scientific process in a comprehensive hands-on manner, and gain research experience that will prepare them to pursue careers in neurobiology or other related STEM fields. The intense interest this work has generated in the pilot stages indicates that the incorporated educational outreach programs will help address a serious need for science education, particularly among Arkansas grade school students, where approximately 40% of those assessed perform below basic achievement levels (2011 Nation's Report Card, National Assessment of Educational Programs, U.S. Department of Education).
了解大脑如何组织成专门的区域(触觉,运动,视觉等)对于理解大脑如何发育,以及它们如何在发育障碍或损伤后受到影响和潜在修复至关重要。 一个更好地了解大脑组织的有效策略是检查具有独特身体结构和行为的哺乳动物。这些研究的目的是利用解剖学和电生理学记录方法来表征九带犰狳(Dasypus novemcinctus)大脑区域的组织和功能。 该项目将揭示哺乳动物神经系统如何处理专门的感觉输入。犰狳全身覆盖着骨质板,高度依赖听觉。这些特征预计会影响负责触觉,运动和听觉的大脑区域;理解这种关系将有助于了解其他哺乳动物(如人类)的类似系统。除了拥有感官特化,犰狳还独特地生出相同的四胞胎(基本上是克隆),为相关的神经发育研究提供了与相同的同窝仔进行比较的平台,这是任何其他哺乳动物发育模型都无法实现的理想实验情况。这些研究将在中央阿肯色州大学进行,涉及对本科生和硕士生进行尖端神经生物学研究方法的培训,其中许多人是第一代大学生。参与的学生将以全面的实践方式参与科学过程,并获得研究经验,为他们从事神经生物学或其他相关STEM领域的职业做好准备。这项工作在试点阶段产生的浓厚兴趣表明,纳入的教育推广计划将有助于解决科学教育的严重需求,特别是在阿肯色州小学生中,其中约40%的被评估学生的表现低于基本成绩水平(2011年国家成绩单,国家教育计划评估,美国教育部)。

项目成果

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Jeffrey Padberg其他文献

Evolution of Association Pallial Areas: Parietal Association Areas in Mammals
关联皮质区的进化:哺乳动物的顶叶关联区
  • DOI:
  • 发表时间:
    2009
  • 期刊:
  • 影响因子:
    0
  • 作者:
    Jeffrey Padberg
  • 通讯作者:
    Jeffrey Padberg
Hand Use and the Evolution of Posterior Parietal Cortex in Primates
灵长类动物的手部使用和后顶叶皮层的进化
  • DOI:
    10.1016/b0-12-370878-8/00040-9
  • 发表时间:
    2007
  • 期刊:
  • 影响因子:
    0
  • 作者:
    L. Hinkley;Jeffrey Padberg;L. Krubitzer;E. Disbrow
  • 通讯作者:
    E. Disbrow
2.19 – Xenarthran Nervous Systems
2.19 – Xenarthran 神经系统
  • DOI:
    10.1016/b978-0-12-804042-3.00053-1
  • 发表时间:
    2017
  • 期刊:
  • 影响因子:
    0
  • 作者:
    Jeffrey Padberg
  • 通讯作者:
    Jeffrey Padberg

Jeffrey Padberg的其他文献

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