Collaborative Research: ABI Development: Enabling discovery across disciplines through a synthesis of time-calibrated evolutionary histories

协作研究：ABI 开发：通过综合时间校准的进化历史实现跨学科发现

• 批准号: 1262440
• 负责人: Sudhir Kumar
• 金额: $ 57.86万
• 依托单位: Arizona State University
• 依托单位国家: 美国
• 项目类别: Continuing Grant
• 财政年份: 2013
• 资助国家: 美国
• 起止时间: 2013-08-01 至 2014-07-31
• 项目状态: 已结题
• 来源: https://www.nsf.gov/awardsearch/showAward?AWD_ID=1262440&HistoricalAwards=false
• 关键词: Collaborative; Research; ABI; Development; Enabling

This project builds a tree of life calibrated to geologic time, called a timetree of life. A unified computational knowledge-base (TimeTree) synthesizes the results of published research studies and delivers the timetree of life to scientists and the public at large. That is, everyone will be given easy access to knowledge contained in thousands of individual studies that have reported relationships and divergence times among species. Through graphical visualizations and knowledge integration, TimeTree will enable scientists to generate new insights into biological and other phenomena, including connections between Earth history and the evolution of species. Such cross-disciplinary comparisons have previously led to major discoveries in science, where a pattern in one field (e.g., biology) has been explained by a mechanism in another field (e.g., geology). Timetrees are now widely used in diverse fields and are important for researchers who study biodiversity and conservation, and the threat of environmental change to the survival of species now and in the future.TimeTree is accessible to students and scientists freely through the web, smartphones, and tablets, and is used as an educational tool in the classroom. Anyone with a high school education can use TimeTree to find the time of divergence between two species and be in touch with their evolutionary history. TimeTree facilitates basic research in many areas of science from geology to medicine and genomics. Its unique hierarchical synthesis of the world's timetree data integrates into any database, including the major, global, biological databases and cyber-encyclopedias. TimeTree products are served to researchers through a web interface that facilitates in-depth analyses of well-curated data by the community at large. Work on the database itself involves postdoctoral, graduate student, and undergraduate training. More information about this project can be obtained from http://www.timetree.org.

该项目建立了一棵根据地质时间校准的生命树，称为生命时间树。统一的计算知识库（TimeTree）综合了已发表的研究结果，并向科学家和广大公众提供生命的时间树。也就是说，每个人都可以轻松获取数千项单独研究中包含的知识，这些研究报告了物种之间的关系和分化时间。通过图形可视化和知​​识整合，时间树将使科学家能够对生物和其他现象产生新的见解，包括地球历史和物种进化之间的联系。这种跨学科的比较以前已经导致了科学领域的重大发现，其中一个领域（例如生物学）的模式可以通过另一个领域（例如地质学）的机制来解释。时间树现已广泛应用于各个领域，对于研究生物多样性和保护以及环境变化对现在和未来物种生存的威胁的研究人员来说非常重要。学生和科学家可以通过网络、智能手机和平板电脑免费访问时间树，并在课堂上用作教育工具。任何受过高中教育的人都可以使用 TimeTree 来查找两个物种之间的分歧时间并了解它们的进化历史。 TimeTree 促进了从地质学到医学和基因组学等许多科学领域的基础研究。其对世界时间树数据的独特分层综合可以集成到任何数据库中，包括主要的全球生物数据库和网络百科全书。 TimeTree 产品通过网络界面向研究人员提供服务，该界面有助于整个社区对精心策划的数据进行深入分析。数据库本身的工作涉及博士后、研究生和本科生培训。有关该项目的更多信息可以从 http://www.timetree.org 获取。