Adhesion and Translocation of Nanoparticles through Lipid Membranes
纳米粒子通过脂质膜的粘附和易位
基本信息
- 批准号:1264702
- 负责人:
- 金额:$ 35万
- 依托单位:
- 依托单位国家:美国
- 项目类别:Standard Grant
- 财政年份:2013
- 资助国家:美国
- 起止时间:2013-08-15 至 2018-07-31
- 项目状态:已结题
- 来源:
- 关键词:
项目摘要
The PI lays out a number of outstanding issues in lipid-NP interactions that he proposes to address via molecular simulations using an original mesoscale simulation technique using ?ghost tweezers? as a method to explore the energy landscape of interfacial interactions of lipid membranes with nanoparticles. If successful, the project can provide important insights for as varied fields as biomedical imaging, drug delivery, lipid-mediated synthesis of nanoparticles, and biosensing with nanoparticle-lipid bilayers systems.
PI列出了一些悬而未决的问题,在脂质NP的相互作用,他建议通过分子模拟使用原始的中尺度模拟技术,使用?鬼镊子作为探索脂质膜与纳米颗粒的界面相互作用的能量景观的方法。如果成功,该项目可以为生物医学成像,药物输送,脂质介导的纳米颗粒合成以及纳米颗粒-脂质双层系统的生物传感等不同领域提供重要见解。
项目成果
期刊论文数量(0)
专著数量(0)
科研奖励数量(0)
会议论文数量(0)
专利数量(0)
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Alexander Neimark其他文献
Modeling temperature-dependent 2D phase behavior and elastic properties of lung surfactant monolayers at air-water interfaces using dissipative particle dynamics simulations
- DOI:
10.1016/j.bpj.2023.11.305 - 发表时间:
2024-02-08 - 期刊:
- 影响因子:
- 作者:
Kolattukudy P. Santo;Monica Iepure;Yuanzhong Zhang;Younjin Min;Alexander Neimark - 通讯作者:
Alexander Neimark
2115 ENDOVASCULAR SUPERSELECTIVE EMBOLIZATION OF PROSTATIC ARTERIES AS THE NEW METHOD OF BPH LESS INVASIVE TREATMENT
- DOI:
10.1016/j.juro.2011.02.2311 - 发表时间:
2011-04-01 - 期刊:
- 影响因子:
- 作者:
Ivan Dedov;Dmitry Kurbatov;Ivan Sitkin;Alexander Neimark;Ekaterina Yakovets;Alexander Lepetuhin;Sergey Dubsky - 通讯作者:
Sergey Dubsky
Adsorption of pulmonary surfactants on the spike proteins of SARS-CoV-2 and its variants
- DOI:
10.1016/j.bpj.2023.11.2867 - 发表时间:
2024-02-08 - 期刊:
- 影响因子:
- 作者:
Kolattukudy P. Santo;Ryan Jaworski;Alexander Neimark - 通讯作者:
Alexander Neimark
Acoustic force spectroscopy reveals subtle differences in interfacial protein-polysaccharide binding interactions
- DOI:
10.1016/j.bpj.2023.11.992 - 发表时间:
2024-02-08 - 期刊:
- 影响因子:
- 作者:
Shishir P.S. Chundawat;Markus Hackl;Cesar A. Lopez;Kolattukudy P. Santo;Sandrasegaram Gnanakaran;Alexander Neimark - 通讯作者:
Alexander Neimark
Alexander Neimark的其他文献
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{{ truncateString('Alexander Neimark', 18)}}的其他基金
Multiscale Modeling of Coronavirus Virions in the Respiratory System
呼吸系统中冠状病毒病毒颗粒的多尺度建模
- 批准号:
2138052 - 财政年份:2022
- 资助金额:
$ 35万 - 项目类别:
Continuing Grant
Collaborative Research: Interactions of Airborne Engineered Nanoparticles with Lung Surfactant Films
合作研究:空气传播的工程纳米粒子与肺表面活性剂膜的相互作用
- 批准号:
2040302 - 财政年份:2020
- 资助金额:
$ 35万 - 项目类别:
Continuing Grant
Collaborative Research: Deformation of poroelastic nanoporous materials of hierarchical structure upon adsorption of gas mixtures: theory, molecular modeling and experiments
合作研究:分级结构多孔弹性纳米多孔材料吸附气体混合物时的变形:理论、分子建模和实验
- 批准号:
1834339 - 财政年份:2018
- 资助金额:
$ 35万 - 项目类别:
Standard Grant
GOALI: Theoretical Foundations of Interaction Nanoparticle Chromatography
GOALI:相互作用纳米颗粒色谱的理论基础
- 批准号:
1510993 - 财政年份:2015
- 资助金额:
$ 35万 - 项目类别:
Standard Grant
Travel support for the 12th International Conference on Fundamentals of Adsorption
第十二届吸附基础国际会议的差旅费支持
- 批准号:
1551591 - 财政年份:2015
- 资助金额:
$ 35万 - 项目类别:
Standard Grant
Mesoscale modeling of self-assembly and transport in polymer electrolyte membranes
聚合物电解质膜自组装和传输的介观建模
- 批准号:
1207239 - 财政年份:2012
- 资助金额:
$ 35万 - 项目类别:
Continuing Grant
GOALI: Multiscale Modeling of Adsorption Equilibrium and Dynamics in Polymer Chromatography
GOALI:聚合物色谱中吸附平衡和动力学的多尺度建模
- 批准号:
1064170 - 财政年份:2011
- 资助金额:
$ 35万 - 项目类别:
Standard Grant
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