Adhesion and Translocation of Nanoparticles through Lipid Membranes

PI提出了脂质- np相互作用中的一些突出问题，他建议通过使用原始中尺度模拟技术的分子模拟来解决这些问题。鬼镊子吗?作为一种探索纳米颗粒与脂质膜界面相互作用的能量景观的方法。如果成功，该项目可以为生物医学成像、药物输送、纳米颗粒脂质介导合成和纳米颗粒脂质双层系统的生物传感等领域提供重要的见解。

The PI lays out a number of outstanding issues in lipid-NP interactions that he proposes to address via molecular simulations using an original mesoscale simulation technique using ?ghost tweezers? as a method to explore the energy landscape of interfacial interactions of lipid membranes with nanoparticles. If successful, the project can provide important insights for as varied fields as biomedical imaging, drug delivery, lipid-mediated synthesis of nanoparticles, and biosensing with nanoparticle-lipid bilayers systems.