Carbon Nanotubes as an Intracellular Neural Electrode

1265085-DeWees该项目的主要目标是开发一种纳米级电生理探头，能够记录完整大脑中单个神经元及其周围的电活动。该探头将由单个碳纳米管(CNT)或一小束多个碳纳米管组成，这些碳纳米管是从尖锐的钨电极上生长出来的。该装置将被涂上对二甲苯，这将为钨丝和碳纳米管之间的接触提供电气绝缘和结构支撑。这个探头将是迄今为止建造的最小的被动神经记录电极，为许多以前不可能进行的实验和医学应用打开大门。公开摘要这项提议将利用纳米技术开发更灵敏的电极，用于监测大脑中神经细胞的活动。这项新技术将提供有关神经系统疾病的更好信息，并可能导致对此类疾病的更好治疗。

1265085 - DeWeeseThe primary goal of this project is to develop a nanometer-scale electrophysiological probe capable of recording the electrical activity both in and around individual neurons in the intact brain. The probe will consist of a single carbon nanotube (CNT) or a small bundle of multiple CNTs, grown from a sharpened tungsten electrode. The device will be coated with Parylene, which will provide electrical insulation as well as structural support for the contact between the tungsten wire and the CNT. This probe will be the smallest passive neural recording electrode ever built, by far, opening doors to many previously impossible experiments and medicalapplications.Public abstractThis proposal will use nanotechnology to develop more sensitive electrodes for monitoring activity of nerve cells in the brain. This new technology will provide better information about neurological diseases and may lead to better treatment of such diseases.