2013 Biological Mechanisms in Evolution: Basic Biology, Cancer, Infectious Disease & Medicine, June 2 - 7, 2013 at Stonehill College in Easton, MA

2013年6月2日至7日在马萨诸塞州伊斯顿的斯通希尔学院举行的戈登生物机制研究会议：在基础生物学、癌症、传染病和医学中，将带来对生物机制的当前理解，包括基因组可塑性、突变、基于蛋白质和RNA的遗传、表观遗传学、压力、应激反应、随机性、表型变异和可塑性的分子机制，以帮助理解进化以及许多由进化驱动的基础科学问题。进化生物学和机制分子遗传学、基因组学和分子生物学领域将统一起来，重点关注后者对我们理解进化的贡献。二十世纪初的现代合成诞生了现代进化生物学，先于分子生物学革命。传统的进化生物学并不总是跟上遗传遗传的基本假设的变化，以及分子机制研究中发现的非遗传遗传。同样，分子生物学往往忽视了进化在重要的基础生物学问题中的关键作用。这次会议的目标是越来越多的研究人员试图利用分子生物学机制来理解进化。其目标是促进对当今进化机制及其在医学和基础生物学中的后果的综合机械论观点。尽管分子生物学最近才开始渗透到进化生物学的领域，但这些学科的整合对于更深入地理解进化和一般生物学是至关重要的。这次会议将为从事这项工作的研究人员提供一个家和社区。GRC计划将包括由更年轻和更成熟的研究人员邀请和贡献的口头和海报演示，重点是该领域最好的新兴科学。GRC将为与会者提供一种最先进的观点，了解驱动进化的基本生物机制，从而使我们对进化机制的理解发生革命。GRC将促进物理学家和生物学家之间的国际和国家合作，旨在了解基本的分子和生物机制，并将这种理解应用于疾病和基础生物学的进化。它还将为年轻科学家提供网络机会、灵感和联系，为处于职业生涯关键阶段的年轻参与者提供关于尖端新研究的指导和观点。NSF的资金将用于支付不同群体的研究生、博士后、新调查人员以及女性和少数族裔参与者的费用。

The Gordon Research Conference on Biological Mechanisms in Evolution: in Basic Biology, Cancer, Infectious Disease and Medicine, 2-7 June 2013 at Stonehill College, Easton, MA will bring current understanding of biological mechanisms, including molecular mechanisms of genome plasticity, mutagenesis, protein- and RNA-based inheritance, epigenetics, stress, stress responses, stochasticity, and phenotypic variation and plasticity, to bear on understanding of evolution, and many basic-science problems driven by evolution. The fields of evolutionary biology and mechanistic molecular genetics, genomics and molecular biology, focusing on the contributions of the latter to our understanding of evolution will be united. The modern synthesis of the early twentieth century, which gave birth to current evolutionary biology, predated the molecular biology revolution. Traditional evolutionary biology has not always kept pace with changes to the basic assumptions of genetic inheritance and discoveries of non-genetic inheritance that have come from studies on molecular mechanisms. Similarly, molecular biology has often ignored the critical roles of evolution in important basic-biological problems. This meeting is aimed at the growing body of investigators attempting to bring molecular biological mechanisms to bear on understanding of evolution. The goals are to catalyze integrated, mechanistic views of mechanisms of evolution operating today and their consequences in medicine and basic biology. Although molecular biology is only recently beginning to penetrate the arena of evolutionary biology, integration of these disciplines is crucial for deeper understanding of evolution and biology in general. This meeting will give a home and community to researchers doing this. The GRC program will include invited and contributed oral and poster presentations by both younger and more established researchers, focusing on the best emerging science in the field. The GRC will provide participants a state-of-the-art view of a revolution in our understanding of the mechanisms of evolution brought about by understanding the fundamental biological mechanisms that drive it. The GRC will promote international and national collaboration between physicists and biologists, aimed at understanding fundamental molecular and biological mechanisms, and bringing this understanding to bear on evolution in disease and basic biology. It will also provide networking opportunities, inspiration and connections for young scientists, mentoring, and perspectives on cutting-edge new research for younger participants at a critical stage in their careers. The NSF funds will be used to defray the costs of a diverse group of graduate students, postdocs, new investigators and women and minority participants particularly.