RCN: Integrating and Coordinating a National and International Plant, Algae, and Microbial Metabolomics Research Coordination Network

RCN：整合和协调国家和国际植物、藻类和微生物代谢组学研究协调网络

• 批准号: 1340058
• 负责人: Lloyd Sumner
• 金额: $ 49.98万
• 依托单位: Noble Research Institute, LLC
• 依托单位国家: 美国
• 项目类别: Standard Grant
• 财政年份: 2013
• 资助国家: 美国
• 起止时间: 2013-09-01 至 2017-08-31
• 项目状态: 已结题
• 来源: https://www.nsf.gov/awardsearch/showAward?AWD_ID=1340058&HistoricalAwards=false
• 关键词: RCN; Integrating; Coordinating; National; International

US Participants: Lloyd W. Sumner (Samuel Roberts Noble Foundation); Oliver Fiehn (University of California, Davis), James Liao (University of California, Los Angeles), Georg Jander (Boyce Thompson Institute), Basil Nikolau (Iowa State University), Richard A. Dixon (University of North Texas), Jean S. VanderGheynst (University of California, Davis), John Labavitch (University of California, Davis), Tobias Kind (University of California, Davis), William Wikoff (University of California, Davis), Alisa Huffaker (USDA-ARS, Gainsville), and Eric Schmelz (USDA-ARS, Gainsville)Japan Participants: Kazuki Saito (Riken Plant Science Center), Masanori Arita (University of Tokyo), Eiichiro Fukusaki (Osaka University), Yutaka Okumoto (Kyoto University), Kazuo Shinozaki (Riken Plant Science Center), Jun Kikuchi (Riken Plant Science Center), Mami Yamazaki (Chiba University), Hideyuki Suzuki (Kazusa DNA Research Institute), Daisaku Ohta (Osaka Prefecture University), Shigehiko Kanaya (NAIST), Hiroshi Shimizu (Osaka University), Fumio Matsuda (Osaka University), Naoki Mori (Kyoto University), Naoko Yoshinaga (Kyoto University), and Yutaka Okumoto (Kyoto University)The primary goal of this project is to develop a Plant, Algae and Microbial Metabolomics Research Coordination Network (PAMM NET) that will promote effective communication, enhance opportunities for collaboration, build community consensus, identify key challenges in metabolomics, and facilitate coordinated community empirical efforts to meet these challenges. Participation in PAMM NET will be open to the public, and will begin with the unification of four independent and international projects funded through the joint NSF-JST Metabolomics for a Low Carbon Society program. This unification will further amplify NSF's current investment in plant, algae and microbial metabolomics, and will be achieved through regular videoconferences and annual face-to-face program meetings and workshops. This team will serve as a nucleus to build forth a more unified national and international PAMM NET that will identify and pursue solutions to the key challenges that still impede the full potential of metabolomics. This will be facilitated through the recruitment of a network coordinator who will serve as a dedicated advocate for the organization, facilitate integration, and provide logistical support for consensus reporting of the network outcomes. The initial nucleus and the network coordinator will then recruit public participants from the US and global plant, algae, and microbial metabolomics communities to build working focus groups. These focus groups will actively discuss the current grand challenges associated with metabolomics and potential solutions to these challenges. The PAMM NET recognizes that many challenges will need the involvement of the larger biology, technology, and bioinformatics communities and PAMM NET will therefore recruit feedback and active participation from these diverse groups to best formulate empirical solutions to the grand challenges. PAMM NET will further contribute to the development of a US National Chapter of the Metabolomics Society to better serve and provide long-term solutions for the needs of the US metabolomics community. PAMM NET will build a repartee with other federally funded programs such as the NIH-supported National Metabolomics Centers to better coordinate efforts across federal funding divisions and scientific disciplines. Finally, PAMM NET will initiate conversations with the global metabolomics community to identify and pursue cooperative international metabolomics funding opportunities. A coordinated community effort is expected to be more cordial, efficient, and productive, thereby leading to new and enabling scientific discoveries and innovations. The PAMM NET RCN considers research-based education and training as an integral part of preparing young scientists for fruitful careers. Accordingly, the PAMM NET will encourage, coordinate and support the attendance of early-career scientists (young faculty, graduate students, post-docs and a limited number of undergraduate students) at annual workshops that are associated with each of the NSF-JST Metabolomics programmatic projects through a limited number of scholarships. These programmatic workshops will include hands-on demonstrations of different aspects of metabolomics research that will range from the use of sophisticated chromatographic, mass-spectrometric and NMR-based tools for metabolite analysis, to computational and statistical analyses and interpretation of metabolomics data. In addition, this RCN will organize and support an annual workshop associated with international plant biology or metabolomics meetings (e.g., Annual Meeting of the Metabolomics Society or the Annual Meeting of the American Society of Plant Biologists). Information about the activities of the PAMM NET will be housed at the project website (to be developed) and the resources generated will be transferred to the Metabolomics Society website for long-term maintenance and support.

美国参与者：Lloyd W. Sumner（塞缪尔·罗伯茨诺贝尔基金会）； Oliver Fiehn（加州大学戴维斯分校）、James Liao（加州大学洛杉矶分校）、Georg Jander（博伊斯汤普森研究所）、Basil Nikolau（爱荷华州立大学）、Richard A. Dixon（北德克萨斯大学）、Jean S. VanderGheynst（加州大学戴维斯分校）、John Labavitch（加州大学戴维斯分校）、Tobias Kind（加州大学戴维斯分校） 加利福尼亚大学戴维斯分校）、William Wikoff（加利福尼亚大学戴维斯分校）、Alisa Huffaker（美国农业部农业研究局，盖恩斯维尔）和 Eric Schmelz（美国农业部农业研究局，盖恩斯维尔） 日本参与者：Kazuki Saito（理研植物科学中心）、Masanori Arita（东京大学）、Eiichiro Fukusaki（大阪大学）、Yutaka Okumoto (京都大学)、Kazuo Shinozaki (理化学研究所植物科学中心)、Jun Kikuchi (理化学研究所植物科学中心)、Mami Yamazaki (千叶大学)、Hideyuki Suzuki (Kazusa DNA 研究所)、Daisaku Ohta (大阪府立大学)、Shigehiko Kanaya (NAIST)、Hiroshi Shimizu (大阪) 大学）、Fumio Matsuda（大阪大学）、Naoki Mori（京都大学）、Naoko Yoshinaga（京都大学）和 Yutaka Okumoto（京都大学）该项目的主要目标是开发一个植物、藻类和微生物代谢组学研究协调网络（PAMM NET），该网络将促进有效沟通，增加合作机会，建立社区共识，确定关键技术 代谢组学的挑战，并促进协调社区实证工作以应对这些挑战。 PAMM NET 的参与将向公众开放，并将首先通过 NSF-JST 低碳社会代谢组学联合计划资助的四个独立国际项目进行统一。 此次统一将进一步扩大 NSF 目前在植物、藻类和微生物代谢组学方面的投资，并将通过定期视频会议和年度面对面计划会议和研讨会来实现。 该团队将作为建立更加统一的国家和国际 PAMM NET 的核心，该网络将识别并寻求解决方案，以应对仍然阻碍代谢组学充分发挥潜力的关键挑战。 这将通过招聘一名网络协调员来促进，该协调员将作为该组织的专门倡导者，促进整合，并为网络成果的共识报告提供后勤支持。 然后，最初的核心和网络协调员将招募来自美国和全球植物、藻类和微生物代谢组学社区的公众参与者，以建立工作焦点小组​​。 这些焦点小组将积极讨论当前与代谢组学相关的重大挑战以及这些挑战的潜在解决方案。 PAMM NET 认识到，许多挑战需要更大的生物学、技术和生物信息学社区的参与，因此 PAMM NET 将招募这些不同群体的反馈和积极参与，以最好地制定应对重大挑战的经验解决方案。 PAMM NET 将进一步为代谢组学协会美国国家分会的发展做出贡献，以更好地服务美国代谢组学界的需求并提供长期解决方案。 PAMM NET 将与其他联邦资助的项目（例如 NIH 支持的国家代谢组学中心）建立一个对答关系，以更好地协调联邦资助部门和科学学科的工作。 最后，PAMM NET 将发起与全球代谢组学界的对话，以确定并寻求国际代谢组学合作资助机会。 协调一致的社区努力预计将更加诚恳、高效和富有成果，从而带来新的、有利的科学发现和创新。 PAMM NET RCN 认为以研究为基础的教育和培训是培养年轻科学家取得富有成果的职业生涯的一个组成部分。 因此，PAMM NET 将通过数量有限的奖学金，鼓励、协调和支持早期职业科学家（年轻教师、研究生、博士后和有限数量的本科生）参加与每个 NSF-JST 代谢组学计划项目相关的年度研讨会。 这些专题研讨会将包括代谢组学研究不同方面的实践演示，范围从使用复杂的色谱、质谱和核磁共振工具进行代谢物分析，到计算和统计分析以及代谢组学数据的解释。此外，该 RCN 将组织和支持与国际植物生物学或代谢组学会议（例如代谢组学协会年会或美国植物生物学家协会年会）相关的年度研讨会。有关 PAMM NET 活动的信息将存放在项目网站（待开发），产生的资源将转移到代谢组学协会网站以进行长期维护和支持。