CAREER: Contact Charge Electrophoresis for Mobile Microfluidics

最近发现的一种新型电泳——接触电荷电泳（CCEP）很有趣，但其本身并没有广泛的用途，因为这种现象会导致带电粒子或液滴在两个电极之间振荡。PI已经绘制了如何打破振荡和线性化运动的路线图，通过使用“棘轮”通过长距离移动粒子，并使用棘轮在微流体装置中分离粒子。他还制定了计划，利用新的模拟工具了解CCEP的基本机制，并在他的实验室验证他的模型。这种操纵小颗粒的新能力将对许多技术产生额外的影响，例如那些需要颗粒分离或用于电子显示、细胞分选和DNA测序的技术。

Bishop1351704The recent discovery of a new type of electrophoresis, contact-charge electrophoresis (CCEP), is interesting, but is not broadly useful per se in that the phenomenon results in a charged particle or droplet oscillating between two electrodes. The PI has drawn out a roadmap of how to break out of the oscillation and linearize the motion by using "ratchets" to move the particles through long distances and to use the ratchets to separate particles in microfluidic devices. He has also laid out plans to understand the basic mechanism of CCEP using new simulation tools and to validate his models in his laboratory. This new ability to manipulate small particles will have an additional impact on many technologies such as those that require particle separations or technologies used in electronic displays, cell sorting, and DNA sequencing.