Fabrication of Novel Core-Shell Nanocomposites as Targeted Carriers

点击翻译按钮获取中文摘要

This project intends to design and fabricate a group of core-shell nanocomposites as new-generation carriers for effective drug delivery applications. The unique core-shell functional materials possess radiation/magnetic-responsive release behaviour due to the nanoparticle core, and good biocompatibility, ultra-high loading capacity and outstanding targeting specificity due to the surface-modified mesoporous metal-organic frameworks shell. Development of such hybrid materials would overcome the existing challenges such as low loading capacity, poor release control. The application of such materials may help to improve the efficacy of pharmaceutical therapies.