NSF Postdoctoral Fellowship in Biology FY 2014

2014 财年 NSF 生物学博士后奖学金

• 批准号: 1400787
• 负责人: Ross Cunning
• 金额: $ 13.8万
• 依托单位: Cunning Ross
• 依托单位国家: 美国
• 项目类别: Fellowship Award
• 财政年份: 2015
• 资助国家: 美国
• 起止时间: 2015-02-01 至 2017-01-31
• 项目状态: 已结题
• 来源: https://www.nsf.gov/awardsearch/showAward?AWD_ID=1400787&HistoricalAwards=false
• 关键词: NSF; Postdoctoral; Fellowship; Biology; FY

NSF Postdoctoral Fellowships in Biology combine research and training components to prepare young scientists for careers in emerging areas where biology intersects with other scientific disciplines, in this case with mathematics. The Fellows are expected to lead the nation's scientific workforce of the future. This fellowship to Ross Cunning supports research and training to integrate quantitative genetic and modeling approaches to understand climate change impacts on coral symbiosis. The host institutions for the Fellowship are the University of Hawaii and the University of California, Santa Barbara; the sponsoring scientists are Drs. Ruth Gates and Roger Nisbet. Training goals include genomics, bioinformatics, and dynamic energy budget theory and modeling techniques to examine the coral-zooxanthellae symbiosis. Educational outreach to students in Hawaii includes students from groups under-represented in STEM fields. The research seeks to understand the dynamic interactions between reef-building corals and their symbiotic algae in an era of global environmental change. The future persistence of coral reef ecosystems depends on the integrity of this symbiosis; stress disrupts the symbiosis, but the processes underlying its regulation and stability, even in the absence of environmental stress, are poorly understood. The approach is to extract molecular information from corals and sea anemones with zooxanthellae raised under various conditions, then model the results and test the outcomes of the models, resulting in a mechanistic understanding of the maintenance and breakdown of symbiosis and integrate "omics"-based molecular data within a Dynamic Energy Budget (DEB) model for coral symbiosis. The specific aims are to 1) develop a comprehensive DEB framework to model coral-algal symbiotic interactions, 2) assess environmental influences on symbiosis structure and function with quantitative metagenomic and transcriptomic datasets, and 3) integrate these data within the DEB modeling framework to test diverse hypotheses regarding the regulation and control of symbiosis and predict responses to complex changes in the environment.

NSF生物学博士后研究金联合收割机结合研究和培训组件，为年轻科学家在生物学与其他科学学科交叉的新兴领域的职业生涯做好准备，在这种情况下与数学。 这些研究员预计将领导国家未来的科学工作者。 罗斯·坎宁的奖学金支持研究和培训，以整合定量遗传和建模方法，了解气候变化对珊瑚共生的影响。 研究金的主办机构是夏威夷大学和加州大学圣巴巴拉分校;赞助科学家是Ruth Gates博士和Roger Nisbet博士。 培训目标包括基因组学，生物信息学和动态能量预算理论和建模技术，以研究珊瑚虫黄藻共生关系。 对夏威夷学生的教育推广包括来自STEM领域代表性不足的群体的学生。该研究旨在了解在全球环境变化的时代，造礁珊瑚及其共生藻类之间的动态相互作用。珊瑚礁生态系统未来的持久性取决于这种共生关系的完整性;压力破坏了共生关系，但即使在没有环境压力的情况下，对其调节和稳定性的基本过程也知之甚少。 该方法是从珊瑚和海葵中提取分子信息，并在各种条件下饲养虫黄藻，然后对结果进行建模，并测试模型的结果，从而对共生的维持和分解进行机械理解，并将基于“组学”的分子数据整合到珊瑚共生的动态能量预算（DEB）模型中。具体目标是：1）开发一个全面的DEB框架来模拟珊瑚-藻类共生相互作用，2）评估环境对共生结构和功能的影响，并使用定量宏基因组和转录组数据集，以及3）将这些数据整合到DEB建模框架中，以测试有关共生调控的各种假设，并预测对环境复杂变化的响应。