RAPID: COLLABORATIVE RESEARCH: Fate and Transport of Antibiotics and Antibiotic Resistance Genes During Historic Colorado Flood

快速：合作研究：历史性科罗拉多洪水期间抗生素和抗生素抗性基因的命运和运输

• 批准号: 1402651
• 负责人: Amy Pruden
• 金额: $ 1.8万
• 依托单位: Virginia Polytechnic Institute and State University
• 依托单位国家: 美国
• 项目类别: Standard Grant
• 财政年份: 2013
• 资助国家: 美国
• 起止时间: 2013-12-15 至 2015-11-30
• 项目状态: 已结题
• 来源: https://www.nsf.gov/awardsearch/showAward?AWD_ID=1402651&HistoricalAwards=false
• 关键词: RAPID; COLLABORATIVE; RESEARCH; Fate; Transport

1402651PrudenRecently it has come to the attention of the scientific community and to the public that pharmaceutical compounds are being found in many natural waters, for example, streams, rivers, lakes and sometimes groundwater. The U.S. Centers for Disease Control and Prevention, the World Health Organization, and numerous other global and national agencies have recognized that one potential implication of these findings is that bacterial normally found in natural water may develop resistance to the antibiotics. This may be one of the most critical challenges of this century. Studies have shown that antibiotic resistant bacteria can be selected, maintained, and transported within various environmental compartments, by environmental compartments we mean streams and rivers. This project seeks to explore the impact of the recent flooding in Colorado on what is referred to as mobilization of pharmaceuticals (the partitioning of pharmaceutical compounds from sediments to the flowing water) and to investigate whether or not there is an increase in antibiotic resistance in these organisms associated with these waters. With a database of 10 years in the South Platte River the research team is well positioned to conduct additional sampling. This project will be supporting graduate and undergraduate students from three participating universities and will be used for the students as part of undergraduate independent research or graduate student thesis and dissertations.

最近，科学界和公众注意到，在许多天然沃茨中发现了药物化合物，例如溪流、河流、湖泊，有时还有地下水。 美国疾病控制和预防中心，世界卫生组织和许多其他全球和国家机构已经认识到，这些发现的一个潜在含义是，通常在天然水中发现的细菌可能会对抗生素产生耐药性。 这可能是本世纪最严峻的挑战之一。 研究表明，抗生素耐药性细菌可以在各种环境隔室中选择，维持和运输，我们指的是溪流和河流。 该项目旨在探讨最近在科罗拉多洪水对所谓的药物动员（药物化合物从沉积物到流动的水的分配）的影响，并调查是否有增加与这些沃茨相关的这些生物体的抗生素耐药性。 有了南普拉特河10年的数据库，研究小组有能力进行额外的采样。 该项目将支持来自三所参与大学的研究生和本科生，并将作为本科生独立研究或研究生论文和论文的一部分用于学生。