SBIR Phase I: Enhanced Biocatalytic Selenium Removal from Water and Wastewater

SBIR 第一阶段：增强生物催化从水和废水中除硒

• 批准号: 1416565
• 负责人: Joseph Salanitro
• 金额: $ 15万
• 依托单位: Microvi Biotech Inc
• 依托单位国家: 美国
• 项目类别: Standard Grant
• 财政年份: 2014
• 资助国家: 美国
• 起止时间: 2014-07-01 至 2015-04-30
• 项目状态: 已结题
• 来源: https://www.nsf.gov/awardsearch/showAward?AWD_ID=1416565&HistoricalAwards=false
• 关键词: SBIR; Phase; Enhanced; Biocatalytic; Selenium

The broader impact/commercial potential of this project will be the availability of a new low-cost, high performance technology to remove selenium from water, thereby contributing to national goals for protecting public health and maintaining natural ecosystems. While selenium is an essential trace element, excess selenium can lead to hair and skin changes, gastrointestinal symptoms, and damage to nervous, kidney and liver tissue. Selenium levels as low as 1.5 parts-per-billion result in toxic bioaccumulation in aquatic life, endangering the food chain and ecosystem balance. While existing regulations limit selenium concentrations in water to 50 parts-per-billion, industrial effluents (e.g. flue gas desulfurization, mining wastewater, coal power plants) are often required to achieve levels below 10 parts-per-billion. Meeting these very low limits is often unachievable or prohibitively expensive using existing technologies. In preliminary results, the proposed technology shows promise as an intensified, targeted, robust, and high performance biological treatment technology with substantially lower projected costs compared to the state-of-the-art. This is the first time that a technology for selenium removal combines novel methods in microorganism culture development with materials science, which helps further our understanding of how technical innovation along interdisciplinary lines can be applied for alleviating such widespread problems as selenium pollution.This Small Business Innovation Research Phase I project is a multidisciplinary approach to respond to a widespread and increasing market demand for more effective, reliable and cost-efficient technologies for removing selenium from water and wastewater. While a variety of chemical, biological, and physical methods exist to remove selenium from water, high costs and increasingly stringent regulation drive an effort for new technologies. This first component of this work investigates selenium biotransformation and applies state-of-the-art techniques in microorganism culture development. Following culture development, novel synthetic biocatalyst composites with specific functionalities are developed as a method for deploying and enhancing the robustness of the technology application. Finally, a prototype of the biocatalytic technology is constructed and thoroughly tested to evaluate industrially- and economically-relevant operating parameters. The proposed Phase I work assesses the feasibility and suitability of the new selenium treatment technology, including determination of microbial characteristics, kinetic parameters, and process design. Overall, this project stands to advance our understanding of microbial selenium reduction, provide an improved process for industrial wastewater treatment, and demonstrate the effectiveness of multidisciplinary collaboration for applied technologies in the water and wastewater treatment sector.

该项目更广泛的影响/商业潜力将是获得一种新的低成本、高性能的技术来从水中去除硒，从而有助于实现保护公众健康和维护自然生态系统的国家目标。虽然硒是一种必需的微量元素，但过量的硒会导致头发和皮肤的变化，胃肠道症状，以及对神经、肾脏和肝脏组织的损害。低至百万分之1.5的硒水平会导致有毒生物在水生生物中积累，危及食物链和生态系统平衡。虽然现有法规将水中的硒浓度限制在十亿分之五十，但工业废水(如烟气脱硫、采矿废水、燃煤电厂)往往被要求达到十亿分之十以下的水平。使用现有技术，达到这些非常低的限制通常是无法实现的，或者成本高得令人望而却步。在初步结果中，拟议的技术显示出作为一种强化的、有针对性的、健壮的和高性能的生物处理技术的前景，与最先进的生物处理技术相比，预计成本大幅降低。这是首次将微生物培养开发的新方法与材料科学相结合的除硒技术，这有助于我们进一步了解如何应用跨学科的技术创新来缓解像硒污染这样的普遍问题。这个小企业创新研究第一阶段项目是一个多学科的方法，以响应广泛和日益增长的市场需求，即更有效、更可靠、更具成本效益的水和废水中的除硒技术。虽然存在各种化学、生物和物理方法来去除水中的硒，但高昂的成本和日益严格的监管推动了对新技术的努力。这项工作的第一个组成部分是研究硒的生物转化，并将最先进的技术应用于微生物培养开发。随着培养技术的发展，具有特定功能的新型合成生物催化剂复合材料被开发为一种部署和增强技术应用的稳健性的方法。最后，构建了生物催化技术的原型，并对其进行了彻底的测试，以评估与工业和经济相关的操作参数。拟议的第一阶段工作评估新的硒处理技术的可行性和适宜性，包括微生物特性、动力学参数和工艺设计的确定。总体而言，该项目将促进我们对微生物降硒的理解，为工业废水处理提供改进的工艺，并展示水和废水处理领域应用技术的多学科合作的有效性。