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EAGER: Cooperative Spectroscopy for Real-time In Vivo Nano-biosensing: Towards Health-centric Smartphones

EAGER：用于实时体内纳米生物传感的合作光谱：迈向以健康为中心的智能手机

基本信息

批准号：
1445934
负责人：
Josep Jornet
金额：
$ 29.99万
依托单位：
SUNY at Buffalo
依托单位国家：
美国
项目类别：
Standard Grant
财政年份：
2014
资助国家：
美国
起止时间：
2014-07-15 至 2016-12-31
项目状态：
已结题

来源：
https://www.nsf.gov/awardsearch/showAward?AWD_ID=1445934&HistoricalAwards=false
关键词：
EAGER Cooperative Spectroscopy Real time

项目摘要

Proposal: 1445934PI: Jornet, JosepInstitution: SUNY at Buffalo EAGER: Cooperative Spectroscopy for Real-time In Vivo Nano-biosensing: Towards Health-centric SmartphonesSignificance:The project is expected to pave the way for the development of in vivo nanosensors networks for biosensing applications with direct application to the next generation of health-centric smartphones and wearable devices. This technology has the potential to radically change current disease diagnosis and treatment techniques. The idea of improving the accuracy of existing diagnostic techniques based on individual nano-biosensors by utilizing a distributed network of coordinated nano-devices, is transformative. This project contributes to a much wider and ambitious vision of advanced health-monitoring and drug delivery systems, using a novel interdisciplinary approach to leverage and combine the state-of-the-art in nano-biosensing, wireless communication and networks, as well as distributed data collection and signal processing.Intellectual Description:The objective of the proposed research is to prove the feasibility of cooperative spectroscopy for real-time in vivo nano-biosensing applications. The ultimate goal is to replace the external independent excitation and measurement system used in classical spectroscopy by a network of coordinated nano-devices, able to both excite and measure the response of nano-biofunctional particles. The benefits of this approach are several. First, the much smaller size and lower power requirements than classical spectroscopy systems will allow the integration of the proposed platform in the next generation of health-centric smartphones as well as new types of wearable devices. Second, the placement of the nanodevices in close contact with the entity to measure on a fingerprint touch scanner or eventually inside the human body, allows for the transmission and detection of low-power, low-noise signals. Third, the collection of the received signal at different nano-devices that collaborate with each other, allows for much more accurate sensing using advanced signal processing for distributed data collection.

提案：1445934PI：Jornet，Josep 机构：纽约州立大学布法罗分校 EAGER：实时体内纳米生物传感的合作光谱：迈向以健康为中心的智能手机意义：该项目预计将为生物传感应用的体内纳米传感器网络的开发铺平道路，并直接应用于下一代以健康为中心的智能手机和可穿戴设备设备。这项技术有可能从根本上改变当前疾病的诊断和治疗技术。通过利用协调纳米设备的分布式网络来提高基于单个纳米生物传感器的现有诊断技术的准确性的想法是变革性的。该项目采用新颖的跨学科方法来利用和结合纳米生物传感、无线通信和网络以及分布式数据收集和信号处理领域的最先进技术，为先进健康监测和药物输送系统的更广泛和雄心勃勃的愿景做出了贡献。智力描述：拟议研究的目的是证明实时体内纳米生物传感合作光谱的可行性应用程序。最终目标是用协调纳米设备网络取代经典光谱学中使用的外部独立激发和测量系统，能够激发和测量纳米生物功能颗粒的响应。这种方法的好处有很多。首先，比传统光谱系统更小的尺寸和更低的功率要求将允许将所提出的平台集成到下一代以健康为中心的智能手机以及新型可穿戴设备中。其次，将纳米器件放置在与实体紧密接触的位置，以便在指纹触摸扫描仪上或最终放置在人体内部进行测量，从而可以传输和检测低功耗、低噪声信号。第三，在相互协作的不同纳米设备上收集接收到的信号，可以使用先进的信号处理进行分布式数据收集，从而实现更准确的传感。

项目成果

期刊论文数量（11）

专著数量（0）

科研奖励数量（0）

会议论文数量（0）

专利数量（0）

Modeling and Performance Analysis of Metallic Plasmonic Nano-Antennas for Wireless Optical Communication in Nanonetworks

用于纳米网络无线光通信的金属等离子体纳米天线的建模和性能分析

DOI：
10.1109/access.2017.2690990
发表时间：
2017
期刊：
IEEE Access
影响因子：
3.9
作者：
Nafari, Mona;Jornet, Josep Miquel
通讯作者：
Jornet, Josep Miquel

An optofluidic channel model for in vivo nanosensor networks in human blood

人体血液体内纳米传感器网络的光流控通道模型

DOI：
10.1117/12.2262824
发表时间：
2017
期刊：
SPIE Proceedings
影响因子：
0
作者：
Hall, Russell D.;Blowers, Misty;Williams, Jonathan;Johari, Pedram;Jornet, Josep M.
通讯作者：
Jornet, Josep M.

Cooperative Raman Spectroscopy for Real-Time In Vivo Nano-Biosensing

用于实时体内纳米生物传感的协作拉曼光谱