SBIR Phase I: An Electronically Activated Antimicrobial Catheter

SBIR 第一阶段：电子激活抗菌导管

• 批准号: 1519499
• 负责人: Paul Robertson
• 金额: $ 15万
• 依托单位: Puratec LLC
• 依托单位国家: 美国
• 项目类别: Standard Grant
• 财政年份: 2015
• 资助国家: 美国
• 起止时间: 2015-07-01 至 2016-06-30
• 项目状态: 已结题
• 来源: https://www.nsf.gov/awardsearch/showAward?AWD_ID=1519499&HistoricalAwards=false
• 关键词: SBIR; Phase; Electronically; Activated; Antimicrobial

This Small Business Innovation Research Phase I project advances a new approach for reducing infection rates associated with medical devices. The global urinary catheters market in 2013 was estimated at $2.4 billion, and the United States market was $1.1 billion. The average resulting healthcare system treatment cost related to catheter-associated urinary tract infections (CAUTIs) is estimated between $500 and $1,000 for each infection or between $500 million and $1 billion annually for the total market. This project will support development of a Foley catheter that is expected to significantly reduce the incidence of these CAUTIs. The intellectual merit of this project is the development of a novel technology that results in the release of a high concentration of antimicrobial silver ions near the surface of the device. In this project, we will generate an antimicrobial Foley catheter that incorporates the company's proprietary technology so as to provide for significantly improved antimicrobial control compared to existing devices. The objective of this Phase I project is to produce an electronically activated catheter that will provide a minimum of 3-log additional reduction in bacterial count over the current market-leading antimicrobial catheter, for all bacterial species tested.

这个小型企业创新研究第一阶段项目提出了一种降低与医疗器械相关的感染率的新方法。2013年，全球导尿管市场规模估计为24亿美元，美国市场规模为11亿美元。与导管相关性尿路感染(CAUTIs)相关的医疗系统治疗成本平均估计为每种感染500至1,000美元，或整个市场每年5亿至10亿美元。该项目将支持Foley导管的开发，预计将显著减少这些CAUTIs的发生率。该项目的智能优点是开发了一种新技术，可以在设备表面附近释放高浓度的抗菌银离子。在这个项目中，我们将生产一种结合了该公司专有技术的抗菌Foley导管，以提供与现有设备相比显著改进的抗菌控制。该第一阶段项目的目标是生产一种电子激活导管，与目前市场领先的抗菌导管相比，对于所有被测试的细菌种类，该导管将至少额外减少3个对数的细菌数量。