Dynamics of Electronically Excited States - Biomolecules in the Gas Phase

电子激发态动力学 - 气相生物分子

• 批准号: 0615755
• 负责人: David Pratt
• 金额: $ 52.96万
• 依托单位: University of Pittsburgh
• 依托单位国家: 美国
• 项目类别: Continuing Grant
• 财政年份: 2006
• 资助国家: 美国
• 起止时间: 2006-09-15 至 2009-08-31
• 项目状态: 已结题
• 来源: https://www.nsf.gov/awardsearch/showAward?AWD_ID=0615755&HistoricalAwards=false
• 关键词: Dynamics; Electronically; Excited; States; Biomolecules

In this award, funded by the Experimental Physical Chemistry Program of the Chemistry Division, Prof. David W. Pratt of the University of Pittsburgh and his graduate and undergraduate research students will conduct high resolution spectroscopic measurements of gas phase biomolecules. His group will look at a variety of "push-pull" molecules, the chromophore of green fluorescent protein, short peptide and nucleic acid sequences, and water clusters of the above. Some of the specific techniques to be used include Stark spectroscopy and chirped-pulse Fourier-transform microwave spectroscopy. The ultimate goals of these studies are to gain a deeper understanding of the photophysics of prototypical biomolecular species and to provide accurate data for theoretical chemists interested in biomolecular problems. Besides the broader scientific impacts of the research being supported, Prof. Pratt continues to provide excellent scientific training to his undergraduate and graduate research students, and he is actively involved in developing curricular materials for undergraduates not majoring in the sciences and he is working with the University of Pittsburgh's Learning & Research Development Center, the School of Education and the Pittsburgh Board of Public Education to provide professional development opportunities for middle school science teachers.

在这个由化学系实验物理化学计划资助的奖项中，大卫W。匹兹堡大学的普拉特和他的研究生和本科生研究生将进行气相生物分子的高分辨率光谱测量。 他的小组将研究各种“推拉”分子、发色团的绿色荧光蛋白、短肽和核酸序列，以及上述的水分子簇。 将使用的一些具体技术包括斯塔克光谱和啁啾脉冲傅里叶变换微波光谱。 这些研究的最终目标是获得原型生物分子物种的物理学的更深入的理解，并提供准确的数据，对生物分子问题感兴趣的理论化学家。除了支持研究的更广泛的科学影响外，Pratt教授继续为他的本科生和研究生提供优秀的科学培训，他积极参与为非科学专业的本科生开发课程材料，他正在与匹兹堡大学的学习&研究发展中心合作，教育学院和匹兹堡公共教育委员会为中学科学教师提供专业发展机会。