Application of Amplitude/Phase Modulated Pulses for Dipolar EPR Spectroscopy
Application of Amplitude/Phase Modulated Pulses for Dipolar EPR Spectroscopy
批准号:
221296566
负责人:
Professor Dr. Thomas F. Prisner
金额:
$0.0万
依托单位国家:
德国
项目类别:
Priority Programmes
财政年份:
2012
资助国家:
德国
项目状态:
已结题
起止时间:
2011-12-31 至 2019-12-31
中文摘要
在这个项目中,我们希望基于幅/相位调制宽带脉冲开发新的偶极光谱脉冲序列。这包括一个新的CPMG (Carr-Purcell / meiboomm - gill) PELDOR(脉冲电子-电子双共振)序列,它具有延长的观测时间窗口,一个宽带2D-SIFTER(单频技术重聚焦偶极耦合)脉冲序列,用于在偶极时间迹中编码方向信息的刚性自旋标签,以及一个DQC(双量子相干)实验,它可能扩展到多量子滤波实验。这将为确定膜蛋白复合物在特定条件下寡聚态的变化提供有价值的工具。此外,我们想探索这种脉冲序列在非常高的磁场(9.2 T)下的可能性。
英文摘要
In this project we want to develop new pulse sequences for dipolar spectroscopy based on amplitude/phase modulated broadband pulses. This includes a new CPMG (Carr-Purcell / Meiboom-Gill) PELDOR (Pulsed Electron Electron Double Resonance) sequence, which exhibits a prolonged observation time window, a broadband 2D-SIFTER (Single Frequency Technique for Refocusing of Dipolar Coupling) pulse sequence for rigid spin labels with orientation information encoded in the dipolar time traces and a DQC (Double Quantum Coherence) experiment, which might be extended to multiple-quantum filter experiments, which would be valuable tools for determining the change of oligomeric states of membrane protein complexes under specific conditions. Additionally we want to explore the possibility of such pulse sequences at very high magnetic fields (9.2 T).
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批准号:208504338
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项目类别:Research Grants
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资助金额:$0.0万
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负责人:Professor Dr. Thomas F. Prisner
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依托单位:
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依托单位:
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财政年份:--
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依托单位:
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财政年份:--
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负责人:Professor Dr. Thomas F. Prisner
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依托单位:
海外基金