MRI: Acquisition of a 3-Tesla Magnetic Resonance Imaging (MRI) Scanner for Human Brain Imaging

该奖项为坦普尔大学在首席研究员Jason Chein的指导下购买高性能3特斯拉（3T）全身磁共振成像（MRI）扫描仪提供支持，所需的硬件和软件。仪器将在促进建立一个新的，多模态，行为研究成像中心在坦普尔大学（TU）主校区发挥核心作用。这台扫描仪将专门用于研究和研究教育，服务于一个大型的，多学科，社区的研究人员从坦普尔和邻近机构，目前缺乏获得最先进的MRI资源。MRI已成为行为和生物行为科学的重要工具。该工具使研究人员能够非侵入性地研究大脑的结构组织和指示大脑功能的血氧水平依赖（BOLD）信号的局部变化。有了这些信息，研究人员可以推断具有高空间分辨率的神经活动，表征脑组织的体积差异，准确跟踪大脑中连接通路的组织，并破译大脑整体激活曲线中所代表的复杂模式，从而为人类如何思考，记忆，决策和注意力的突破性新发现打开了大门。它提供了对人类如何处理语言，空间和行动以及这些能力如何发展的洞察力。本申请中要求的仪器是Siemens WITTTOM Prisma 3T扫描仪，将提供行业领先的成像能力，具有令人印象深刻的信噪比、成像速度以及空间和时间分辨率。购置这套磁共振成像系统，将使本地科学家能够扩展他们所从事的研究范围，并开拓新的研究领域，这些领域是目前有限的成像资源所无法支持的。一个新的3T MRI系统的收购也将加强研究生和本科教育坦普尔？它是高度多样化的城市校园。主校区MRI研究中心的建立也将极大地影响吸引顶尖科学家和学生的努力。

This awards provides support for Temple University under the direction of Principal Investigator Jason Chein to purchase a high-performance 3-Tesla (3T) whole-body Magnetic Resonance Imaging (MRI) scanner, required hardware and software. The instrumentation will play a central role in facilitating the establishment of a new,multi-modal, behavioral research imaging center on the Temple University (TU) Main Campus.This scanner will be devoted exclusively to research and research education, serving a large,multi-disciplinary, community of investigators from Temple and neighboring institutions that presently lack access to state-of-the-art MRI resources. MRI has become an essential tool in behavioral and bio-behavioral science. This tool enables researchers to study, non-invasively, both the structural organization of the brain and the local changes in the blood oxygen level dependent (BOLD) signal that index brain function. With this information, researchers can infer neural activity with high spatial resolution, characterize volumetric differences in brain tissue, accurately track the organization of connective pathways in the brain, and decipher complex patterns represented in the brain's overall activation profile, thus opening the door to ground-breaking new discoveries pertaining to how humans think, remember, make decisions, and pay attention. It provides insight into how humans process language, space, and action and how these capabilities develop. The instrument requested in this application, a Siemens MAGNETOM Prisma 3T scanner, will provide industry- leading imaging capabilities, with impressive signal-to-noise ratios, imaging speed, and spatial and temporal resolution. Acquisition of this MRI system will enable local scientists to extend the reach of the research they are engaged in and to develop pioneering new lines of investigation that are not supported by the limited imaging resources currently available. The acquisition of a new 3T MRI system will also enhance graduate and undergraduate education on Temple?s highly diverse, urban campus. The establishment of a main campus MRI research center will also substantially impact efforts to attract top scientists and studentsto the institution.