MRI: Acquisition of a 3-Tesla Magnetic Resonance Imaging (MRI) Scanner for Human Brain Imaging

这项奖励为天普大学在首席研究员Jason Chein的指导下购买高性能3-Tesla(3T)全身磁共振成像(MRI)扫描仪以及所需的硬件和软件提供支持。该仪器将在促进在天普大学(TU)主校区建立一个新的、多模式的行为研究成像中心方面发挥核心作用。这台扫描仪将专门用于研究和研究教育，为来自天普大学和邻近机构的大型、多学科、研究人员社区提供服务，这些机构目前无法获得最先进的核磁共振资源。核磁共振已经成为行为和生物行为科学中必不可少的工具。这一工具使研究人员能够非侵入性地研究大脑的结构组织和指示大脑功能的血氧水平依赖(BOLD)信号的局部变化。有了这些信息，研究人员可以推断出高空间分辨率的神经活动，表征脑组织的体积差异，准确跟踪大脑中连接路径的组织，并破译大脑整体激活模式中代表的复杂模式，从而为有关人类如何思考、记忆、决策和注意力的开创性新发现打开大门。它提供了对人类如何处理语言、空间和动作以及这些能力是如何发展的洞察力。本申请要求的仪器是西门子Magnetom Prisma 3T扫描仪，它将提供业界领先的成像功能，具有令人印象深刻的信噪比、成像速度以及空间和时间分辨率。收购这一核磁共振成像系统将使当地科学家能够扩大他们从事的研究的范围，并开发目前有限的成像资源无法支持的开创性新研究路线。收购新的3T磁共振系统也将加强寺庙？S高度多样化的城市校园的研究生和本科生教育。建立一个主校园核磁共振研究中心也将对吸引顶尖科学家和学生进入该机构的努力产生重大影响。

This awards provides support for Temple University under the direction of Principal Investigator Jason Chein to purchase a high-performance 3-Tesla (3T) whole-body Magnetic Resonance Imaging (MRI) scanner, required hardware and software. The instrumentation will play a central role in facilitating the establishment of a new,multi-modal, behavioral research imaging center on the Temple University (TU) Main Campus.This scanner will be devoted exclusively to research and research education, serving a large,multi-disciplinary, community of investigators from Temple and neighboring institutions that presently lack access to state-of-the-art MRI resources. MRI has become an essential tool in behavioral and bio-behavioral science. This tool enables researchers to study, non-invasively, both the structural organization of the brain and the local changes in the blood oxygen level dependent (BOLD) signal that index brain function. With this information, researchers can infer neural activity with high spatial resolution, characterize volumetric differences in brain tissue, accurately track the organization of connective pathways in the brain, and decipher complex patterns represented in the brain's overall activation profile, thus opening the door to ground-breaking new discoveries pertaining to how humans think, remember, make decisions, and pay attention. It provides insight into how humans process language, space, and action and how these capabilities develop. The instrument requested in this application, a Siemens MAGNETOM Prisma 3T scanner, will provide industry- leading imaging capabilities, with impressive signal-to-noise ratios, imaging speed, and spatial and temporal resolution. Acquisition of this MRI system will enable local scientists to extend the reach of the research they are engaged in and to develop pioneering new lines of investigation that are not supported by the limited imaging resources currently available. The acquisition of a new 3T MRI system will also enhance graduate and undergraduate education on Temple?s highly diverse, urban campus. The establishment of a main campus MRI research center will also substantially impact efforts to attract top scientists and studentsto the institution.