Collaborative Research: Modeling-Based Design of Freeze-Cast Hybrid Materials

合作研究：基于建模的冷冻铸造混合材料设计

• 批准号: 1538094
• 负责人: Ulrike G K Dr Wegst
• 金额: $ 36.13万
• 依托单位: Dartmouth College
• 依托单位国家: 美国
• 项目类别: Standard Grant
• 财政年份: 2015
• 资助国家: 美国
• 起止时间: 2015-09-01 至 2019-08-31
• 项目状态: 已结题
• 来源: https://www.nsf.gov/awardsearch/showAward?AWD_ID=1538094&HistoricalAwards=false
• 关键词: Collaborative; Research; Modeling; Based; Design

The freeze-casting process is one with which bulk materials and entire components of several cubic centimeters in size can be manufactured with ease. The process is based on the solidification of water-based solutions or slurries (suspensions). To freeze-cast a scaffold, a solution or slurry is poured into a mold and then directionally solidified. During freezing, the water solidifies in the form of pure ice crystals, and the polymer that was dissolved and the particles that were suspended in this liquid carrier are concentrated between them. Once frozen, the sample is freeze-dried to sublime the ice-phase and reveal the material scaffold; its architecture is the negative of the ice crystals which templated it. The cell wall material structure is the result of a self-assembly process. Freeze casting or "ice templating" is a relatively inexpensive procedure and provides a means to mimic complex, efficient natural materials with hierarchical designs over several length-scales. This award supports research to build models, basic design principles and tools that will enable a systematic approach for the design and manufacture of freeze-cast hybrid materials with enhanced performance. These new materials will be of benefit to both individuals and the general public at large through applications that range from energy generation and storage to tissue repair and regeneration.This research program focuses on the fundamental science and modeling-driven design of freeze-cast hybrid materials. An interdisciplinary team with expertise in modeling, experiment and characterization will address current knowledge gaps and analyze the formation and evolution of the ice phase and ice-templated material architectures generated by the freeze casting process in an attempt to uncover basic physicochemical principles and determine fundamental processing-structure-property correlations. The three research goals are to (1) determine the underlying fundamental materials science and establish a realistic model for ice-crystal nucleation and growth on a well-defined substrate (graphene) during freeze casting; (2) uncover processing-structure-property correlations by combining multiscale computational modeling with experimental approaches; and (3) develop predictive models to identify the most promising processing-additive combinations in order to custom-design and optimize structure formation and performance in the model material system.

冷冻铸造工艺是一种可以轻松制造几立方厘米大小的散装材料和整个组件的工艺。该方法基于水基溶液或浆料（悬浮液）的固化。为了冷冻铸造支架，将溶液或浆料倒入模具中，然后定向固化。在冷冻过程中，水以纯冰晶的形式凝固，溶解的聚合物和悬浮在该液体载体中的颗粒浓缩在它们之间。一旦冷冻，样品被冷冻干燥以升华冰相并显示材料支架;其结构是冰晶的负模板。细胞壁材料结构是自组装过程的结果。冷冻铸造或“冰模板”是一种相对便宜的程序，并提供了一种方法来模仿复杂的，有效的天然材料与层次设计超过几个长度尺度。该奖项支持研究建立模型，基本设计原则和工具，这将使一个系统的方法，设计和制造具有增强性能的冷冻铸造混合材料。这些新材料将通过从能量产生和储存到组织修复和再生的应用对个人和公众都有好处。该研究计划侧重于冷冻铸造混合材料的基础科学和模型驱动设计。 一个具有建模、实验和表征专业知识的跨学科团队将解决当前的知识差距，并分析冷冻铸造工艺产生的冰相和冰模板材料结构的形成和演变，试图揭示基本的物理化学原理并确定基本的过程-结构-性质相关性。本研究的三个目标是：（1）确定基础材料科学和建立一个在明确定义的基底上冰晶成核和生长的现实模型（2）通过将多尺度计算建模与实验方法相结合来揭示加工-结构-性质的相关性;和（3）开发预测模型以识别最有希望的加工添加剂组合，以便定制设计和优化模型材料体系中的结构形成和性能。