RII Track-2 FEC: Innovative, Broadly Accessible Tools for Brain Imaging, Decoding, and Modulation

非技术说明此研究基础设施改进 Track-2 重点 EPSCoR* 合作 (RII Track-2 FEC) 项目涉及三个州：罗德岛州、俄克拉荷马州和肯塔基州。该项目将由罗德岛大学牵头，与布朗大学沃伦阿尔珀特医学院/罗德岛医院、肯塔基大学、肯塔基州立大学、俄克拉荷马大学诺曼分校、俄克拉荷马大学健康科学中心和劳瑞德脑研究所合作。参与者将组成一个跨学科联盟，以：1）开发创新且可广泛使用的脑成像和调制技术和工具，以获取有关神经系统在健康和疾病中如何发挥作用的基本见解； 2）培养多元化的劳动力队伍，特别是初级教师，以创建和实施这些技术和工具。这些工具旨在更全面地了解大脑动态活动如何产生动作，并开发针对神经和认知障碍的有效治疗方法。罗德岛团队专注于硬件开发，而肯塔基州和俄克拉荷马州团队则开发算法并实现可从该项目开发的集成系统中受益的应用程序。技术描述研究人员将加速三极同心环电极脑电图的开发，并将其与功能性近红外光谱和经颅聚焦电刺激相结合，以创建便携式、多模式脑成像和刺激系统。 该项目旨在实现将这些技术结合到混合设备中的潜力，这些设备可以利用每种模式的优势来获得更全面的大脑活动和行为图像。除了数据采集之外，该项目还将开发新颖的算法，从自然条件下记录的数据中提取有关大脑功能的信息。这些方法与基础和临床研究相关，并应用于神经科学、认知科学和认知心理学。 该研究将实现低成本、便携式脑成像和刺激设备以及算法的发明和商业化，从而提高这些技术对更多人群的可及性。该项目还包括培养多元化、训练有素的劳动力队伍的多个组成部分，并提出了一项战略，以参与教育和职业过程的每个重要阶段，涵盖从 K-12、本科生、研究生、博士后到初级教师。*刺激竞争性研究的实验计划

Non-technical descriptionThis Research Infrastructure Improvement Track-2 Focused EPSCoR* Collaboration (RII Track-2 FEC) project involves three states: Rhode Island, Oklahoma and Kentucky. The project will be led by the University of Rhode Island in partnership with the Warren Alpert Medical School of Brown University/Rhode Island Hospital, the University of Kentucky, Kentucky State University, the University of Oklahoma, Norman, the University of Oklahoma Health Sciences Center, and the Laureate Institute for Brain Research. The participants will form an interdisciplinary consortium to 1) develop innovative and broadly accessible brain imaging and modulation technologies and tools for acquiring fundamental insight about how the nervous system functions in health and disease; and 2) develop a diverse workforce, with particular emphasis on junior faculty, to create and implement these technologies and tools. These tools are aimed at establishing a more comprehensive understanding of how actions emerge from the dynamic activities in the brain and developing effective treatments for neurological and cognitive impairment. The Rhode Island team focuses on hardware development while the Kentucky and Oklahoma teams develop algorithms and implement applications that could benefit from the integrated systems developed by the project.Technical descriptionThe investigators will accelerate development of tripolar concentric ring electrode electroencephalography, and integrate it with functional near-infrared spectroscopy and transcranial focal electrical stimulation to create a portable, multimodal brain imaging and stimulation system. This project seeks to realize the potential for combining these techniques into hybrid devices that can take advantage of the strengths of each modality to obtain a more comprehensive picture of brain activity and behavior. Besides data acquisition, the project will also develop novel algorithms to extract information about brain functions from data recorded in naturalistic conditions. The methods are relevant to basic and clinical studies, with applications in neuroscience, cognitive science and cognitive psychology. The research will allow the invention and commercialization of low-cost, portable brain imaging and stimulation devices as well as algorithms that will increase accessibility of these technologies to a greater segment of the population. The project also includes multiple components to develop a diverse, well-trained workforce, and presents a strategy to engage each important phase of the education and career process, spanning from K-12, undergraduate, graduate, postdoctoral, to junior faculty.*Experimental Program to Stimulate Competitive Research