EAGER-NEON: Collaborative Research: Formation of a NEON Microbial Metagenomics Data Synthesis Working Group

EAGER-NEON：合作研究：成立 NEON 微生物宏基因组数据合成工作组

• 批准号: 1550852
• 负责人: Folker Meyer
• 金额: $ 17.35万
• 依托单位: University of Chicago
• 依托单位国家: 美国
• 项目类别: Standard Grant
• 财政年份: 2015
• 资助国家: 美国
• 起止时间: 2015-10-01 至 2018-09-30
• 项目状态: 已结题
• 来源: https://www.nsf.gov/awardsearch/showAward?AWD_ID=1550852&HistoricalAwards=false
• 关键词: EAGER; NEON; Collaborative; Research; Formation

The goal of this collaborative project is to enhance the ability to analyze microbial metagenomics datasets of the National Ecological Observatory Network (NEON). Microbial metagenomics, the characterization of microbial communities by the genes present in the sample, is important for fully understanding microbial processes. This project will enhance the comparative analytical capabilities available to the scientific community for describing properties of microbial communities, which will enable better integration of biological and geoscience data with other current earth-systems observing efforts. These improved analytic tools will facilitate developing better interconnections between environmental factors, biogeochemical processes, and microbial ecosystem structure and function in a more holistic fashion. The project will establish a Synthesis Working Group that will collect community input for guiding cyber-infrastructure and bioinformatics tool development and for answering fundamental questions with the NEON microbial metagenomics data sets. This collaborative project will form and coordinate a Synthesis Working Group for analysis and integration of NEON metagenomics data, leveraging ongoing development of bioinformatics and cyber-infrastructure tools for metagenomic data in partnership with other concurrent earth-systems observing efforts EarthCube and Critical Zone Observatories. The Synthesis Working Group will enhance scientific advancement by 1) facilitating formation of a diverse team to inform and utilize NEON microbial metagenomic data, 2) exploring strategies for synthesis of NEON metagenomic data using existing and new bioinformatics and cyberinfrastructure tools, and 3) synthesizing NEON metagenomic datasets via integration with multiple existing and developing open data archives. This project will enable comparisons that cannot be adequately synthesized today, which is necessary for evaluating the sustainability and resilience of microbial ecosystems, as well as the function of these microbial communities in supporting key ecosystem services. The project will engender broad scientific dissemination, use, and intercomparison of NEON data products through targeted scientific outreach activities and engagement of the scientific community, including integration of NEON with other earth-systems observing efforts.

该合作项目的目标是增强分析国家生态观测站网络（NEON）微生物宏基因组数据集的能力。 微生物宏基因组学，即通过样本中存在的基因来表征微生物群落，对于充分理解微生物过程非常重要。该项目将增强科学界描述微生物群落特性的比较分析能力，这将使生物和地球科学数据与其他当前地球系统观测工作更好地整合。这些改进的分析工具将有助于以更全面的方式在环境因素、生物地球化学过程以及微生物生态系统结构和功能之间建立更好的相互联系。该项目将建立一个综合工作组，收集社区意见，以指导网络基础设施和生物信息学工具的开发，并利用 NEON 微生物宏基因组数据集回答基本问题。该合作项目将组建并协调一个综合工作组，用于分析和整合 NEON 宏基因组数据，与其他同时进行的地球系统观测工作 EarthCube 和关键区域天文台合作，利用正在进行的宏基因组数据生物信息学和网络基础设施工具的开发。合成工作组将通过以下方式促进科学进步：1) 促进组建多元化团队来提供和利用 NEON 微生物宏基因组数据；2) 探索使用现有和新的生物信息学和网络基础设施工具合成 NEON 宏基因组数据的策略；3) 通过与多个现有和正在开发的开放数据档案集成来合成 NEON 宏基因组数据集。该项目将实现目前无法充分综合的比较，这对于评估微生物生态系统的可持续性和恢复力以及这些微生物群落在支持关键生态系统服务方面的功能是必要的。该项目将通过有针对性的科学推广活动和科学界的参与，包括将 NEON 与其他地球系统观测工作相结合，促进 NEON 数据产品的广泛科学传播、使用和相互比较。