REU Site: Penn State Cardiovascular Research: Engineering A Translational Experience (CREATE)

REU 网站：宾夕法尼亚州立大学心血管研究：工程转化体验 (CREATE)

• 批准号: 1560064
• 负责人: Keefe Manning
• 金额: $ 39.05万
• 依托单位: Pennsylvania State Univ University Park
• 依托单位国家: 美国
• 项目类别: Standard Grant
• 财政年份: 2016
• 资助国家: 美国
• 起止时间: 2016-03-15 至 2019-02-28
• 项目状态: 已结题
• 来源: https://www.nsf.gov/awardsearch/showAward?AWD_ID=1560064&HistoricalAwards=false
• 关键词: REU; Site; Penn; State; Cardiovascular

This Research Experiences for Undergraduates (REU) Site at Pennsylvania State University-University Park, entitled Penn State Cardiovascular Research: Engineering A Translational Experience (CREATE)," will expose students to research that will elucidate cellular/molecular processes governing biological responses to materials as applied to cardiovascular disease (CVD) and the development of therapeutic CVD interventions. This focus on education in cardiovascular disease (CVD) is extremely important and highly relevant for two reasons. First, CVD remains the number one killer in the United States. Thus, there is a great need to develop a pipeline of new engineers and scientists who can become leaders in the detection, prevention, and treatment of the disease. Second, the underlying etiology of CVD and its associated technologies combine to form a perfect platform for training in the creative and integrative thinking that is the hallmark of biomedical engineering. The objectives of this program are: 1) To conduct research on multi-scale problems to improve the understanding and treatment of CVD, 2) To apply the creative process to solve engineering problems applied to CVD treatment or intervention, 3) To be able to describe the process of translating research into marketable technology, and 4) To be able to identify requirements for success in graduate and professional schools. Over a three year period, this REU program will engage undergraduate students in a 10-week intensive hands-on summer research and professional development/training experience, where they will develop proficiency in the underlying concepts and practice of cellular/molecular engineering, microscopy, or computational methods in biomedical engineering while integrating the creative process towards understanding CVD. The program will include individual research projects with faculty research mentors, seminars on safety training, research needs, and responsible conduct of research, workshops on the creative process applied to research, medical device development and intellectual property, outreach/dissemination of student research, and a research symposium. Through these activities Penn State CREATE will provide young researchers with new avenues of investigation, new technologies in quantitative and analytical methods, and new opportunities in novel diagnostic and interventional tools in medicine.

宾夕法尼亚州立大学-大学公园的本科生研究经验（REU）网站，题为“宾夕法尼亚州立大学心血管研究：工程转化经验（CREATE）”，将使学生接触到研究，阐明细胞/分子过程，这些过程控制对心血管疾病（CVD）和治疗性CVD干预措施的开发材料的生物反应。 这种对心血管疾病（CVD）教育的关注是非常重要和高度相关的，原因有两个。 CVD仍然是美国的头号杀手。 因此，非常需要开发一个新的工程师和科学家的管道，他们可以成为疾病检测，预防和治疗的领导者。其次，CVD的潜在病因及其相关技术联合收割机形成了一个完美的平台，用于培养创造性和综合性思维，这是生物医学工程的标志。该计划的目标是：1）对多尺度问题进行研究，以提高对CVD的理解和治疗，2）应用创造性的过程来解决应用于CVD治疗或干预的工程问题，3）能够描述将研究转化为可销售技术的过程，以及4）能够确定研究生和专业学校成功的要求。 在为期三年的时间里，这个REU计划将让本科生参加为期10周的密集实践夏季研究和专业发展/培训经验，在那里他们将熟练掌握生物医学工程中的细胞/分子工程，显微镜或计算方法的基本概念和实践，同时将创造性过程整合到理解CVD中。 该计划将包括与教师研究导师的个人研究项目，安全培训研讨会，研究需求和负责任的研究行为，应用于研究，医疗器械开发和知识产权，学生研究的推广/传播的创造性过程研讨会，以及研究研讨会。 通过这些活动，宾夕法尼亚州立大学的CREATE将为年轻的研究人员提供新的研究途径，定量和分析方法的新技术，以及新的医学诊断和干预工具的新机会。