REU Site: Penn State Cardiovascular Research: Engineering A Translational Experience (CREATE)

宾夕法尼亚州立大学-大学园区的本科生研究体验(REU)网站题为宾夕法尼亚州立大学心血管研究：工程翻译体验(CREATE)，将向学生展示将阐明细胞/分子过程的研究，这些过程将控制应用于心血管疾病(CVD)的材料的生物反应以及治疗性CVD干预措施的开发。这种对心血管疾病(CVD)教育的关注是极其重要和高度相关的，原因有两个。首先，心血管疾病仍然是美国的头号杀手。因此，非常需要发展一条新的工程师和科学家的管道，他们可以成为这种疾病的检测、预防和治疗的领导者。其次，心血管疾病的潜在病因学及其相关技术结合在一起，形成了一个完美的平台，用于培训生物医学工程的标志--创造性和综合思维。该计划的目标是：1)对多尺度问题进行研究，以提高对CVD的理解和治疗；2)应用创造性的过程来解决应用于CVD治疗或干预的工程问题；3)能够描述将研究转化为市场技术的过程；以及4)能够确定在研究生院和专业学校取得成功的要求。在三年的时间里，这个REU项目将让本科生参加为期10周的强化暑期研究和专业发展/培训体验，在那里他们将熟练掌握细胞/分子工程、显微镜或生物医学工程中的计算方法的基本概念和实践，同时整合了解心血管疾病的创造性过程。该计划将包括与教师研究导师一起的个人研究项目，关于安全培训、研究需求和负责任的研究行为的研讨会，关于应用于研究的创新过程的研讨会，医疗器械开发和知识产权，学生研究的推广/传播，以及研究研讨会。通过这些活动，宾夕法尼亚州立大学CREATE将为年轻研究人员提供新的研究途径、定量和分析方法方面的新技术，以及医学上新的诊断和干预工具的新机会。

This Research Experiences for Undergraduates (REU) Site at Pennsylvania State University-University Park, entitled Penn State Cardiovascular Research: Engineering A Translational Experience (CREATE)," will expose students to research that will elucidate cellular/molecular processes governing biological responses to materials as applied to cardiovascular disease (CVD) and the development of therapeutic CVD interventions. This focus on education in cardiovascular disease (CVD) is extremely important and highly relevant for two reasons. First, CVD remains the number one killer in the United States. Thus, there is a great need to develop a pipeline of new engineers and scientists who can become leaders in the detection, prevention, and treatment of the disease. Second, the underlying etiology of CVD and its associated technologies combine to form a perfect platform for training in the creative and integrative thinking that is the hallmark of biomedical engineering. The objectives of this program are: 1) To conduct research on multi-scale problems to improve the understanding and treatment of CVD, 2) To apply the creative process to solve engineering problems applied to CVD treatment or intervention, 3) To be able to describe the process of translating research into marketable technology, and 4) To be able to identify requirements for success in graduate and professional schools. Over a three year period, this REU program will engage undergraduate students in a 10-week intensive hands-on summer research and professional development/training experience, where they will develop proficiency in the underlying concepts and practice of cellular/molecular engineering, microscopy, or computational methods in biomedical engineering while integrating the creative process towards understanding CVD. The program will include individual research projects with faculty research mentors, seminars on safety training, research needs, and responsible conduct of research, workshops on the creative process applied to research, medical device development and intellectual property, outreach/dissemination of student research, and a research symposium. Through these activities Penn State CREATE will provide young researchers with new avenues of investigation, new technologies in quantitative and analytical methods, and new opportunities in novel diagnostic and interventional tools in medicine.