Meeting: Fourth Topical Meeting on C. elegans Pathogenesis, Aging, Stress, Small RNA, and Metabolism, Madison, Wisconsin, July 21-24,2016

会议：第四届线虫发病机制、衰老、压力、小 RNA 和代谢专题会议，威斯康星州麦迪逊，2016 年 7 月 21-24 日

• 批准号: 1566013
• 负责人: Javier Irazoqui
• 金额: $ 1.35万
• 依托单位: Massachusetts General Hospital
• 依托单位国家: 美国
• 项目类别: Standard Grant
• 财政年份: 2016
• 资助国家: 美国
• 起止时间: 2016-05-01 至 2017-04-30
• 项目状态: 已结题
• 来源: https://www.nsf.gov/awardsearch/showAward?AWD_ID=1566013&HistoricalAwards=false
• 关键词: Meeting; Fourth; Topical; C.; elegans

This award will support participation of under-represented minority graduate students and postdoctoral trainees in the 4th C. elegans Topical Meeting: Pathogenesis, Aging, Stress, Small RNAs, and Metabolism to be held at the University of Wisconsin, Madison, July 21-24, 2016. Nematodes like C. elegans are ubiquitous in nature, and are important ecologically, agriculturally, and medically. Furthermore, insights gleaned from studies of C. elegans interactions with microbes are broadly applicable to many other animals. The meeting draws scientists from many different disciplines, thus proving fertile ground for new inter-disciplinary collaborations and exchange of cutting-edge ideas. As broader impacts, the Meeting is organized by junior faculty members and provides opportunities for graduate students and postdoctoral trainees to present their work, thus providing opportunities for science dissemination and career development, and contributing to a strong U.S. biomedical workforce. The 2016 Meeting provides a novel program, in which break-out sessions are specifically designed to foster communication between distinguished scientists and young trainees. The award will provide support for attendance and presentations by promising young investigators, including women and underrepresented minorities as a focus. In addition dependent day-care will be available on site, which will enhance participation of young investigators, particularly women. NSF-sponsored awards for best poster (undergraduate, graduate, and postdoc categories) and for a new Worm Art show are other key innovations that promote science communication through the visual arts. Results discussed at the meeting will be disseminated to the scientific community by having abstracts accessible online at wormbase.org.As is clear from a large body of work, Host-Microbe Interactions pervade every aspect of host physiology, including its longevity, ability to confront environmental stress, its metabolism, and its epigenetic gene regulation. In any other experimental system, the study of aging, stress responses, epigenetic gene regulation by small RNA, and metabolism are often conducted with little regard for the central relevance of host-microbe interactions. Not so in C. elegans. It is now clear that the insights gleaned from C. elegans host-microbe interaction studies are broadly applicable to many animal species beyond the nematode clade. Comprehensive study of the intricate mechanisms of host-microbe interaction and their consequences on host physiology mandates an experimentally tractable model organism, of which C. elegans is unrivaled. This is the premier meeting focused on host-microbe interactions in stress responses and epigenetics of small RNA in C. elegans.

该奖项将支持代表性不足的少数民族研究生和博士后学员参加第四届C。elegans专题会议：发病机制，衰老，压力，小RNA和代谢将于2016年7月21日至24日在麦迪逊的威斯康星州大学举行。线虫如C.秀丽线虫在自然界中普遍存在，并且在生态、农业和医学上具有重要意义。此外，从C.线虫与微生物的相互作用广泛适用于许多其他动物。会议吸引了来自许多不同学科的科学家，从而为新的跨学科合作和前沿思想的交流提供了肥沃的土壤。作为更广泛的影响，会议由初级教师组织，为研究生和博士后学员提供展示工作的机会，从而为科学传播和职业发展提供机会，并为强大的美国做出贡献生物医学劳动力。2016年的会议提供了一个新颖的计划，其中分组会议专门用于促进杰出科学家和年轻学员之间的交流。该奖项将为有前途的年轻调查人员的出席和演讲提供支持，包括妇女和代表性不足的少数民族作为重点。此外，还将在现场提供受抚养人日托，这将提高年轻调查员，特别是妇女的参与程度。NSF赞助的最佳海报奖（本科生，研究生和博士后类别）和新的蠕虫艺术展是通过视觉艺术促进科学传播的其他关键创新。在会议上讨论的结果将通过在wormbase.org上在线访问摘要传播给科学界。从大量的工作中可以清楚地看到，宿主-微生物相互作用遍及宿主生理学的各个方面，包括其寿命，对抗环境压力的能力，新陈代谢及其表观遗传基因调控。在任何其他实验系统中，对衰老、应激反应、小RNA对表观遗传基因的调控以及代谢的研究往往很少考虑宿主-微生物相互作用的核心相关性。在C中不是这样。优美的现在很清楚，从C。线虫宿主-微生物相互作用的研究广泛适用于线虫分支以外的许多动物物种。对宿主-微生物相互作用的复杂机制及其对宿主生理的影响的全面研究要求建立一种易于实验处理的模式生物，其中C。优雅是无与伦比的。这是第一次会议，重点是宿主-微生物在应激反应中的相互作用和小RNA在C。优雅的。