MRI: Acquisition of a Multinuclear Broadband Cryogenically Cooled Probe for NMR Spectroscopy at KU-Lawrence

堪萨斯大学的贾斯汀·道格拉斯教授及其同事Bala Subramaniam、Mikhail Barybin、Jon Tunge和Ryan Altman在化学研究仪器计划(CRIF)和刺激竞争研究实验计划(EPSCoR)的支持下，获得了用于核磁共振光谱仪(核磁共振)的低温冷却探头。总的来说，核磁共振波谱是化学家可以用来确定分子结构的最强大的工具之一。它被用来识别未知物质，表征分子中原子的特定排列，并研究分子在溶液或固体中相互作用的动力学。对于正在进行前沿研究的化学家来说，获得最先进的核磁共振光谱仪是必不可少的。这些核磁共振研究的结果对合成有机/无机化学、材料化学和生物化学都有影响。为了能够获得数据，核磁共振光谱仪需要一个放置要分析的样品的探头。在低温冷却探测器中，使用非常冷的液体或气体来冷却环境。这种令人不寒而栗的结果显著提高了灵敏度，并在使用较小样本的情况下加快了数据收集速度。该仪器将位于由高素质科学家管理的通用用户设施中。它是大学研究、研究、培训和教学不可或缺的一部分。改进的研究基础设施进一步丰富和促进了该机构目前正在进行的创新努力，以扩大对科学和工程的参与，特别是来自代表性不足群体(例如，性别、族裔、残疾、地理等)的个人。通过将其纳入大学前一级的外展活动。本科生和研究生的课程内容更加丰富。KU学生和参加本科和研究生研究培训计划的其他高校的学生都可以使用新的设施。该奖项旨在加强各级的研究和教育，特别是在以下方面：(A)探索常见官能团的氟化策略；(B)制备天青烯桥接金属有机化合物，作为纳米级电荷离域和运输的平台；(C)专注于催化和反应工程，以利用生物质生产资源高效的化学和燃料，以及(D)通过碳-碳键裂解合成催化剂。

With this award from the Major Research Instrumentation Program (MRI) and support from the Chemistry Research Instrumentation Program (CRIF) as well as the Experimental Program to Stimulate Competitive Research (EPSCoR), Professor Justin Douglas from the University of Kansas and colleagues Bala Subramaniam, Mikhail Barybin, Jon Tunge and Ryan Altman have acquired a cryogenically-cooled probe for a nuclear magnetic resonance spectrometer (NMR). In general, Nuclear Magnetic Resonance (NMR) spectroscopy is one of the most powerful tools available to chemists for determining the structure of molecules. It is used to identify unknown substances, to characterize specific arrangements of atoms within molecules, and to study the dynamics of interactions between molecules in solution or in the solid state. Access to state-of-the-art NMR spectrometers is essential to chemists who are carrying out frontier research. The results from these NMR studies have an impact in synthetic organic/inorganic chemistry, materials chemistry and biochemistry. To be able to obtain data NMR spectrometers require a probe where the sample to be analyzed is placed. In a cryogenically cooled probe, a very cold liquid or gas is used to chill the environment. This chilling results in a significant increase in sensitivity and speeds up data collection while using smaller samples. This instrument to be located in a general user facility managed by highly qualified scientists. It is an integral part of research, research training and teaching at the University. The improved research infrastructure further enriches and facilitates the innovative efforts presently underway at this institution to broaden participation in science and engineering, especially by individuals from underrepresented groups (e. g., gender, ethnicity, disability, geography, etc.) through its integration into outreach at the pre-college level. Coursework at the undergraduate and postgraduate level is enriched. Both KU students and students from other colleges and universities participating in undergraduate and graduate research training programs are able to access the new facilities.The award is aimed at enhancing research and education at all levels, especially in: (a) exploring strategies for fluorination of common functional groups; (b) preparing azulene-bridged organometallics as a platform fo charge delocalization and transport at the nanoscale; (c) focusing on catalysis and reaction engineering for resource-efficient chemical and fuel production from biomass and (d) synthesizing catalyts via carbon-carbon bond cleavage.