MRI: Acquisition of a Multinuclear Broadband Cryogenically Cooled Probe for NMR Spectroscopy at KU-Lawrence

在主要研究仪器项目（MRI）的奖励和化学研究仪器项目（CRIF）以及刺激竞争性研究实验项目（EPSCoR）的支持下，堪萨斯大学的Justin Douglas教授和他的同事Bala Subramaniam、Mikhail Barybin、Jon Tunge和Ryan Altman已经获得了一种用于核磁共振光谱仪（NMR）的低温冷却探针。总的来说，核磁共振（NMR）光谱是化学家用来确定分子结构的最有力的工具之一。它用于识别未知物质，表征分子内原子的特定排列，以及研究溶液或固体状态下分子之间相互作用的动力学。获得最先进的核磁共振光谱仪是必不可少的化学家谁正在进行前沿研究。这些核磁共振研究的结果在合成有机/无机化学、材料化学和生物化学等领域具有重要影响。为了能够获得数据，核磁共振光谱仪需要在待分析样品的位置放置探针。在低温冷却探针中，使用非常冷的液体或气体来冷却环境。这种冷却导致灵敏度显著提高，并在使用较小样本时加快数据收集。该仪器将放置在由高素质科学家管理的一般用户设施中。它是大学研究、研究培训和教学的一个组成部分。改进的研究基础设施进一步丰富和促进了该机构目前正在进行的创新努力，以扩大对科学和工程的参与，特别是来自代表性不足的群体（例如，性别，种族，残疾，地理等）的个人，通过将其整合到大学预科水平的扩展中。丰富了本科和研究生阶段的课程。堪萨斯大学的学生和其他学院和大学参加本科和研究生研究训练项目的学生都可以使用新的设施。该奖项旨在加强各级的研究和教育，特别是在以下方面：(a)探索共同官能团氟化的战略；(b)制备azulene桥接有机金属作为纳米尺度电荷离域和输运的平台；(c)专注于催化和反应工程，用于从生物质中生产资源高效的化学和燃料；(d)通过碳-碳键裂解合成催化剂。

With this award from the Major Research Instrumentation Program (MRI) and support from the Chemistry Research Instrumentation Program (CRIF) as well as the Experimental Program to Stimulate Competitive Research (EPSCoR), Professor Justin Douglas from the University of Kansas and colleagues Bala Subramaniam, Mikhail Barybin, Jon Tunge and Ryan Altman have acquired a cryogenically-cooled probe for a nuclear magnetic resonance spectrometer (NMR). In general, Nuclear Magnetic Resonance (NMR) spectroscopy is one of the most powerful tools available to chemists for determining the structure of molecules. It is used to identify unknown substances, to characterize specific arrangements of atoms within molecules, and to study the dynamics of interactions between molecules in solution or in the solid state. Access to state-of-the-art NMR spectrometers is essential to chemists who are carrying out frontier research. The results from these NMR studies have an impact in synthetic organic/inorganic chemistry, materials chemistry and biochemistry. To be able to obtain data NMR spectrometers require a probe where the sample to be analyzed is placed. In a cryogenically cooled probe, a very cold liquid or gas is used to chill the environment. This chilling results in a significant increase in sensitivity and speeds up data collection while using smaller samples. This instrument to be located in a general user facility managed by highly qualified scientists. It is an integral part of research, research training and teaching at the University. The improved research infrastructure further enriches and facilitates the innovative efforts presently underway at this institution to broaden participation in science and engineering, especially by individuals from underrepresented groups (e. g., gender, ethnicity, disability, geography, etc.) through its integration into outreach at the pre-college level. Coursework at the undergraduate and postgraduate level is enriched. Both KU students and students from other colleges and universities participating in undergraduate and graduate research training programs are able to access the new facilities.The award is aimed at enhancing research and education at all levels, especially in: (a) exploring strategies for fluorination of common functional groups; (b) preparing azulene-bridged organometallics as a platform fo charge delocalization and transport at the nanoscale; (c) focusing on catalysis and reaction engineering for resource-efficient chemical and fuel production from biomass and (d) synthesizing catalyts via carbon-carbon bond cleavage.