RCN: ENSEMBLE (Enabling Neuroscience in Species Models that Broadly Leverage Evolution): A research coordination network advancing strategic development, community building and inn

RCN：ENSEMBLE（广泛利用进化的物种模型中的神经科学）：一个研究协调网络，推进战略发展、社区建设和旅馆

• 批准号: 1638400
• 负责人: Melina Hale
• 金额: $ 34.94万
• 依托单位: University of Chicago
• 依托单位国家: 美国
• 项目类别: Standard Grant
• 财政年份: 2018
• 资助国家: 美国
• 起止时间: 2018-06-01 至 2021-05-31
• 项目状态: 已结题
• 来源: https://www.nsf.gov/awardsearch/showAward?AWD_ID=1638400&HistoricalAwards=false
• 关键词: RCN; ENSEMBLE; Enabling; Neuroscience; Species

Neuroscience research on a full range of animals is essential for long-term progress in understanding the brain. The tremendous diversity in the animal kingdom has given scientists almost endless opportunities to address fundamental questions about brain and behavior. In addition, exploration of the many unique nervous system specializations of organisms will expand perspectives how the nervous system works and, in turn, inspire new designs in engineering. Lastly, an evolutionary framework is essential for interpreting the relationship of structure to function. By building a neuroscience community around research in non-model organisms, one that shares ideas and resources, this research coordination network is expected to advance research in non-model systems broadly, even in ways that reach beyond neuroscience. By leading discussions of key topics for the future of neuroscience, the network is expected to provide expert scientific perspectives to the neuroscience community, policy makers, and others. Communication beyond the scientific community is certain to enhance the public's excitement about neuroscience. Educational opportunities, including lab exchanges, will provide essential training for established scientists and trainees. The development of a network website and outreach programs ensure that network resources and efforts are widely accessible.This research coordination network aims to advance neuroscience in diverse organisms with four main goals: 1. To establish a network that includes broad diversity in the participant scientists, in the taxonomic research systems studied and in institutional location and type. 2. To advance strategic thinking about critical directions for neuroscience performed outside of the five traditional genetic model organisms. Specific topics to be explored include connectomics and the development of reference species. 3. To support and encourage the development and adoption of breakthrough technologies and approaches, including computation, in diverse species and research contexts. 4. To communicate products from both goals 1 and 2 broadly. So as to accomplish these goals, a large, open network of scientists and a website for communicating information and for supporting discussion is being established. Network workshops will bring members together to discuss critical topics in comparative neuroscience. The included educational opportunities aim to facilitate adoption of new techniques outside of the traditional models and encourage collaboration among labs, through workshops and lab exchanges. Products from workshops and other activities are shared widely via the website, publications and other mechanisms. This Research Coordination Network is co-funded by the Modulation Program in the Neural Systems Cluster (NSC) of the Division of Integrative Organismal Systems (IOS), and the Division of Emerging Frontiers (EF).This award reflects NSF's statutory mission and has been deemed worthy of support through evaluation using the Foundation's intellectual merit and broader impacts review criteria.

对各种动物的神经科学研究对于了解大脑的长期进展至关重要。 动物王国的巨大多样性为科学家们提供了几乎无穷无尽的机会来解决有关大脑和行为的基本问题。此外，对生物体许多独特的神经系统专业化的探索将扩大神经系统如何工作的视角，从而激发工程学的新设计。最后，进化框架对于解释结构与功能的关系至关重要。通过围绕非模型生物的研究建立一个神经科学社区，一个共享思想和资源的社区，这个研究协调网络有望广泛地推进非模型系统的研究，甚至以超越神经科学的方式。通过领导对神经科学未来关键主题的讨论，该网络有望为神经科学界、政策制定者和其他人提供专家科学观点。科学界之外的交流肯定会增强公众对神经科学的兴奋。包括实验室交流在内的教育机会将为知名科学家和受训人员提供必要的培训。网络网站的开发和推广计划确保了网络资源和工作的广泛访问。这个研究协调网络旨在推进不同生物体的神经科学，主要目标有四个：1.建立一个网络，其中包括广泛的多样性参与科学家，在分类研究系统的研究和机构的位置和类型。2.推进对五种传统遗传模型生物体之外的神经科学关键方向的战略思考。待探索的具体主题包括连接组学和参考物种的发展。3.支持和鼓励在不同物种和研究背景下开发和采用突破性技术和方法，包括计算。4.广泛宣传目标1和目标2的产品。为了实现这些目标，正在建立一个大型、开放的科学家网络和一个交流信息和支持讨论的网站。网络研讨会将成员聚集在一起，讨论比较神经科学的关键主题。包括的教育机会旨在促进采用传统模式之外的新技术，并通过研讨会和实验室交流鼓励实验室之间的合作。讲习班和其他活动的成果通过网站、出版物和其他机制广泛分享。该研究协调网络由综合有机系统部（IOS）神经系统集群（NSC）的调制计划和新兴前沿部（EF）共同资助。该奖项反映了NSF的法定使命，并通过使用基金会的知识价值和更广泛的影响审查标准进行评估，被认为值得支持。